Related Experiment Video
Updated: Feb 5, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Clinical Characteristics of Patients With Patent Foramen Ovale and Pyogenic Brain Abscess
Khalid Abu-Zeinah1, Pansachee Damronglerd2,3, Hussam Tabaja2
1Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
None:
Patent foramen ovale (PFO) has a prevalence of approximately 25%. Its association with pyogenic brain abscess (PBA) is unclear. We reviewed adults with PBA and known PFO status from 1 January 2009 through 31 December 2021 at Mayo Clinic. High PFO prevalence (40.5%) was seen. PBA patients with PFO had distinct abscess characteristics but unchanged 1-year, all-cause mortality.
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