Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Phase Contrast and Differential Interference Contrast Microscopy

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

Nursing Diagnosis

Nursing Diagnosis

Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

Self-Evaluation: Self-Enhancement and Self-Verification

Self-Evaluation: Self-Enhancement and Self-Verification

Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: A Novel Model for Muscle-Invasive Bladder Cancer Diagnosis Using Contrast-Enhanced Ultrasound.

Annals of surgical oncology·2026

Same author

ASO Author Reflections: Augmenting Contrast-Enhanced Ultrasound: A Quantitative Approach to Predict Muscle-Invasive Bladder Cancer.

Annals of surgical oncology·2026

Same author

Association Between Systemic Immune-Inflammation Index and Thyroid Function: A Cross-Sectional Population-Based Study.

International journal of endocrinology·2026

Same author

Spin radical enhanced magnetocapacitance effect in intermolecular excited states.

The journal of physical chemistry. B·2013

Same author

Recent developments in stir bar sorptive extraction.

Analytical and bioanalytical chemistry·2013

Same author

Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity.

ChemMedChem·2013

Search research articles

Related Experiment Video

Updated: Feb 6, 2026

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

A Novel Model for Muscle-Invasive Bladder Cancer Diagnosis Using Contrast-Enhanced Ultrasound.

Qiping Liu¹, Xuwei Lu², Chang He²

¹Department of Ultrasound, Minhang Hospital, Fudan University, Shanghai, China.

Annals of Surgical Oncology

|February 4, 2026

Summary

This summary is machine-generated.

This study developed a new model combining contrast-enhanced ultrasound (CEUS) radiomics and the Vesical Imaging Reporting and Data System (VI-RADS) score to accurately predict muscle-invasive bladder cancer (MIBC) before surgery.

Keywords:

Bladder cancer Contrast-enhanced ultrasound Muscle-invasive Radiomics

More Related Videos

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Published on: February 11, 2014

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

Related Experiment Videos

Last Updated: Feb 6, 2026

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Minimally Invasive Establishment of Murine Orthotopic Bladder Xenografts

Published on: February 11, 2014

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model

Published on: April 18, 2015

Area of Science:

Radiology
Oncology
Medical Imaging

Background:

Accurate preoperative identification of muscle-invasive bladder cancer (MIBC) is crucial for treatment planning.
Distinguishing MIBC from non-muscle-invasive bladder cancer preoperatively is challenging with current methods.

Purpose of the Study:

To develop and validate a novel predictive model for MIBC.
To integrate contrast-enhanced ultrasound (CEUS) radiomics features with the Vesical Imaging Reporting and Data System (VI-RADS) score.

Main Methods:

Retrospective single-center study of 116 patients with bladder tumors.
Development of a predictive model using CEUS radiomics features and clinical variables (VI-RADS score).
Model validation using training and testing cohorts with XGBoost classifier.

Main Results:

Three CEUS radiomic features and the VI-RADS score were significant predictors of MIBC.
The combined model achieved an area under the curve (AUC) of 0.96, outperforming the radiomic-only model (AUC 0.79).
XGBoost classifier demonstrated superior performance in predicting MIBC.

Conclusions:

A combined model integrating CEUS radiomics and VI-RADS score shows potential for improved preoperative MIBC prediction.
Preliminary validation suggests the model's feasibility and clinical utility in differentiating MIBC.
Further prospective studies are warranted to confirm these findings.