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Related Experiment Video

Updated: Feb 6, 2026

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
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Adaptive sample repulsion against class-specific counterfactuals for explainable imbalanced classification.

Yu Hao1, Xin Gao1, Xinping Diao2

  • 1School of Intelligent Engineering and Automation, Beijing University of Posts and Telecommunications, Beijing, 100876, China.

Neural Networks : the Official Journal of the International Neural Network Society
|February 4, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a novel framework for imbalanced classification that enhances model performance in overlapping feature spaces. The method adaptively repels samples against class-specific counterfactuals, improving classification accuracy and model credibility.

Keywords:
Counterfactual searchExplainable machine learningImbalanced classificationInter-class overlapSample distribution control

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Area of Science:

  • Machine Learning
  • Data Science
  • Artificial Intelligence

Background:

  • Imbalanced classification presents challenges in complex feature spaces with overlapping sample regions.
  • Existing methods often fail to deeply model feature-label relationships or provide instance-level explanations.
  • This limits improvements in classification performance and model credibility.

Purpose of the Study:

  • To propose an explainable imbalanced classification framework (CSCF-SR) that dynamically regulates feature-space distribution.
  • To form a closed-loop between explanation generation and classification decisions using counterfactual samples.
  • To enhance model classification capability for samples in overlapping regions.

Main Methods:

  • A class-specific dual-actor reinforcement learning architecture for counterfactual searching.
  • A multi-step dynamic perturbation mechanism for precise counterfactual sample generation.
  • Adaptive sample repulsion exploiting displacement vectors to clarify class boundaries.

Main Results:

  • CSCF-SR demonstrated superior performance over 27 imbalanced classification methods on F1-score and G-mean across 50 datasets.
  • Significant improvements were observed on 25 datasets with severe class overlap.
  • The framework effectively enhances classification for samples within overlapping regions.

Conclusions:

  • The proposed CSCF-SR framework offers a novel approach to imbalanced classification by integrating explainability and adaptive sample manipulation.
  • The method shows significant performance gains, particularly in challenging scenarios with high class overlap.
  • This work contributes to more credible and accurate imbalanced classification models.