Related Experiment Video
Updated: Feb 6, 2026
Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
Visual performance of spectacle films utilising opaque, non-refractive features for potential myopia management
Jennie Diec1, Daniel Tilia1, Jennifer Sha1
1nthalmic Pty Ltd, Sydney, New South Wales, Australia.
Clinical Relevance:
A non-refractive approach for potential myopia management is introduced as spectacle films with opaque features, hypothesised to modulate retinal ganglion cell activity away from the baseline state of the eye. Visual performance of these spectacle films is currently unknown.
Background:
The aim of this work is to compare the visual performance of spectacle films with opaque non-refractive features (test), MiYOSMART (control: MS), and single vision (control: SV) lenses.
Methods:
This was a prospective, randomised, unmasked, cross-over study where 37 myopic adults (18-42 years) wore each lens for a minimum of 5 days. Subjective visual performance was assessed with a 1-10 numeric rating scale for clarity of vision, vision at night, vision when walking, and overall vision satisfaction and visual acuity (monocular at 6 m and binocular at 6 m and 40 cm). Willingness-to-purchase, based on vision and myopia efficacy, was assessed with a binary Yes/No response.
Results:
Test and SV were rated higher than MS (p ≤ 0.005) for all subjective ratings, while SV was rated higher than test (p ≤ 0.02) for all ratings except vision when walking (p = 0.11). A higher proportion were willing to purchase both test and SV compared to MS based on vision (p ≤ 0.001), with no difference between test and SV (p = 0.20). A higher proportion were willing to purchase SV compared to MS based on myopia efficacy (p = 0.005), with no difference between test and either control (p > 0.06). SV was significantly better than MS for acuity at 40 cm (p = 0.004) with no differences between lenses for other acuity measurements (p > 0.1).
Conclusions:
Test offered better subjective visual performance than MS with higher proportions of participants willing to purchase based on vision. Test offered worse subjective visual performance than SV with no differences in willingness-to-purchase questions. SV offered better visual performance than MS and higher proportions of participants willing to purchase for vision or myopia management.
More Related Videos
Related Concept Videos
01:28Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
01:26Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
01:29Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
01:26Influence of Earth's Curvature and Atmospheric Refraction on Leveling
00:52Potential Energy
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
02:58Cell Potential and Free Energy
Thermodynamics is the branch of physics dealing with the relationship between heat and other forms of energy. In an electrochemical cell, chemical energy is converted into electrical energy.
Thus, a link can be predicted between cell potential, free energy change, and the equilibrium constant for the reaction. Cell potential can also be measured as the oxidant or the reducing strength, and similar acid-base strength measures are reflected in equilibrium...