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Related Experiment Video

Updated: Sep 12, 2025

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia
06:19

Comparison of Three Clinical Stereoscopic Methods for Measuring Binocular Visual Function During Amblyopic Treatment in Unilateral Amblyopia

Published on: September 27, 2024

299

Spatio-Temporal Optical Phase Kit for Myopia Control: Stage 1 Results from a Randomized Controlled Clinical Trial in

Cathleen Fedtke1, Zhi Chen2, Daniel Tilia1

  • 1nthalmic Pty. Ltd., Sydney, Australia; School of Optometry and Vision Science, University of New South Wales, Sydney, Australia.

Ophthalmology
|August 9, 2025
PubMed
Summary

The S.T.O.P. kit, using dynamic optical cues in single vision spectacles, significantly reduced myopia progression in children over six months compared to standard single vision spectacles. Visual performance was maintained, indicating a promising myopia management strategy.

Keywords:
Dynamic optical cueMyopiaOptical filmS.T.O.P.Spectacle lens

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Area of Science:

  • Ophthalmology
  • Optometry
  • Pediatric Eye Care

Background:

  • Myopia, or nearsightedness, is a growing global health concern, particularly in children.
  • Effective myopia control strategies are crucial to prevent high myopia and associated ocular complications.
  • Single vision spectacles (SV) are standard but do not actively manage myopia progression.

Purpose of the Study:

  • To evaluate the efficacy of two S.T.O.P. (dynamic optical cue) kits in mitigating myopia progression in children.
  • To compare the effectiveness of S.T.O.P. kits against traditional single vision spectacles (control).

Main Methods:

  • A prospective, multi-site, double-masked, randomized controlled trial involving 155 children aged 6-14 years with myopia.
  • Participants were randomized to wear either Kit 1, Kit 2, or control (SV spectacles without optical films).
  • Axial length (AL) and cycloplegic refractive error (M) were measured over a 6-month period.

Main Results:

  • Both S.T.O.P. kits demonstrated significantly less axial length elongation compared to the control group after 6 months (Kit 1: 0.083 mm, Kit 2: 0.095 mm vs. Control: 0.169 mm).
  • A significant reduction in myopic refractive error (M) was observed with both S.T.O.P. kits compared to control (Kit 1: -0.189 D, Kit 2: -0.214 D vs. Control: -0.315 D).
  • No significant differences in visual acuity or subjective ratings were found between the groups.

Conclusions:

  • The S.T.O.P. kit, incorporating dynamic optical cues, is an effective intervention for reducing myopia progression in children.
  • This dynamic optical approach shows promise as a novel strategy for myopia management.
  • The S.T.O.P. kit successfully slowed myopia progression without compromising visual performance.