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Published on: June 9, 2023
Racial and ethnic disparities in postnatal growth of infants born before 30 weeks of gestation
Fu-Sheng Chou1,2,3,4, Hung-Wen Yeh5,6, Crystal Hsueh7
1Southern California Permanente Medical Group, Pasadena, CA, USA. Fu-Sheng.X.Chou@kp.org.
Insights
Racial and ethnic disparities affect premature infant growth. Black infants had lower birth weight z-scores but regained weight fastest, while Hispanic infants showed the slowest growth velocity.
Area of Science:
- Neonatology
- Pediatric Growth Studies
- Perinatal Health Disparities
Background:
- Premature infants (<30 weeks gestation) experience unique growth trajectories.
- Understanding racial and ethnic variations in growth is crucial for optimizing care.
- Existing data on disparities in early growth phases for extremely preterm infants is limited.
Purpose of the Study:
- To investigate racial and ethnic disparities in birth weight (BW), time to BW regain, and mean growth velocity.
- To analyze growth patterns in infants born between 23 and 29 weeks' gestation across different racial/ethnic groups.
Main Methods:
- Retrospective analysis of a de-identified dataset (2010-2020) from Pediatrix Medical Group.
- Inclusion of 76,145 infants born between 23-29 weeks gestation.
- Utilized inverse propensity weighting to balance antenatal confounders across racial and ethnic groups (Asian, Hispanic, Black, White, Other).
Main Results:
- Black infants exhibited the lowest BW z-scores compared to White infants, but achieved BW regain fastest.
- Hispanic infants demonstrated the lowest mean growth velocity during the accelerated growth phase.
- Significant racial and ethnic variations were observed in multiple postnatal growth parameters.
Conclusions:
- Postnatal growth disparities in extremely preterm infants are complex and vary by growth phase.
- Racial and ethnic background influences birth weight, weight regain, and growth velocity in preterm neonates.
- Tailored interventions may be necessary to address specific growth challenges faced by different racial and ethnic groups.
Objective:
To assess racial and ethnic disparities in birth weight (BW), time to BW regain, and mean growth velocity during the accelerated weight gain phase.
Study Design:
A retrospective study was conducted using a de-identified dataset from the Pediatrix Medical Group from 2010 to 2020. The dataset categorizes infants into five racial and ethnic groups: Asian, Hispanic, Black, White, and Other, based on maternal report. The study included infants born between 23 and 29 weeks' gestation and excluded infants without weight data.
Results:
This study included 76,145 infants. Antenatal confounders were balanced using inverse propensity weighting. Black infants had lowest, while Hispanic infants had higher BW z-scores, when compared to White infants. Black infants took the shortest time to regain BW. Hispanic infants had the lowest mean growth velocity.
Conclusion:
Racial and ethnic disparities in postnatal growth of infants born before 30 weeks of gestation manifest differently across growth phases.
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