Related Experiment Video
Updated: Feb 6, 2026

12:10
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
9.3K
Robotic Transurethral Vesicourethral Anastomosis after Radical Prostatectomy in Validated Models
Jesse F d'Almeida1, Kimberly A Maciolek2, Ethan Wilke1
1Mechanical Engineering, Vanderbilt University, Nashville, Tennessee, USA.
Journal of Endourology
|February 5, 2026
Summary
This study introduces a novel concentric tube robot (CTR) system for transurethral radical prostatectomy. The CTR system successfully enabled vesicourethral anastomosis in 91% of phantom experiments, overcoming previous limitations.
Area of Science:
- Urology
- Robotic Surgery
- Medical Devices
Background:
- Minimally invasive techniques in radical prostatectomy enhance patient recovery.
- Transurethral prostatectomy aims to reduce surgical dissection but faces challenges in vesicourethral anastomosis.
- Limited instrumentation hinders reliable anastomosis after transurethral prostatectomy.
Purpose of the Study:
- To develop and evaluate a concentric tube robot (CTR) system for transurethral vesicourethral anastomosis.
- To address the limitations of current instrumentation for anastomosis after transurethral prostatectomy.
- To enable a natural-orifice approach to radical prostatectomy.
Main Methods:
- A novel CTR system with needle-sized robotic arms was constructed for transurethral surgery.
- The CTR system utilizes telescoping, curved, elastic tubes for suturing within the urethra.
- System performance was evaluated in validated phantoms for vesicourethral anastomosis after transurethral radical prostatectomy.
Main Results:
- Transurethral radical prostatectomy and anastomosis were performed in 11 phantoms.
- A successful vesicourethral anastomosis was achieved in 10 out of 11 (91%) experiments.
- Median resection time was 19 minutes, and median suturing time was 103 minutes.
Conclusions:
- The CTR system successfully enabled transurethral vesicourethral anastomosis in phantom models.
- This robotic system overcomes a key barrier to natural-orifice radical prostatectomy.
- The CTR facilitates intraluminal completion of the vesicourethral anastomosis.
Related Concept Videos
Reliability and Validity
14.0K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
14.0K
Radical Reactivity: Nucleophilic Radicals
2.7K
Radicals adjacent to electron-donating groups are called nucleophilic radicals. These radicals readily react with electrophilic alkenes. The SOMO–LUMO interactions are the driving force for the reaction, where the high-energy SOMO of the electron-rich, nucleophilic radicals interacts with the low-energy LUMO of the electron-deficient, electrophilic alkenes. Such SOMO–LUMO interactions are the basis of reactive radical traps, affecting the selectivity in radical reactions. For...
2.7K
Radicals
741
Roots, often written as radicals, identify the quantity that must be raised to a specific exponent to produce a given value. A radical expression consists of two main components: the radicand, which is the value placed inside the root symbol, and the index, which indicates the degree of the root being taken. The notation n√a indicates the principal nth root of a. If n equals 2, the operation is the square root, while n = 3 defines the cube root. When n is even, a negative radicand does...
741
Radical Reactivity: Electrophilic Radicals
2.5K
Radicals adjacent to electron‐withdrawing groups are called electrophilic radicals. These radicals readily react with nucleophilic alkenes. For example, the malonate radical, in which the radical center is flanked by two electron‐withdrawing groups, reacts readily with butyl vinyl ether, which consists of an electron‐donating oxygen substituent. The reaction between electrophilic malonate radical and nucleophilic vinyl ether is favored because the radical has a...
2.5K
Data Validation
2.0K
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
2.0K
Data Validation
6.8K
Data validation is an essential part of a comprehensive assessment. Validation is confirming or verifying and opening the door to gathering more assessment data as it clarifies vague or unclear data. The process of checking and verifying the collected information is called data validation. The primary purpose of data validation is to ensure data is as free from error, bias, and misinterpretation as possible.
Nursing assessment guides are generally based on holistic models rather than medical...
Nursing assessment guides are generally based on holistic models rather than medical...
6.8K

