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Updated: Feb 6, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
Radiotherapy combined with bevacizumab in gastrointestinal cancers: Balancing efficacy against the risk of intestinal
Yan Xu1, Xiao-Bing Huang2, Yong-Gang He3
1Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China.
Abstract:
The combination of radiotherapy with bevacizumab represents a promising therapeutic strategy for advanced gastrointestinal cancers. While this combination leverages synergistic mechanisms to enhance antitumor efficacy, it also poses significant safety concerns, particularly regarding the risk of intestinal perforation. This letter discusses the current understanding of this dual effect and underscores the importance of careful patient selection, advanced radiotherapy techniques, and vigilant toxicity monitoring to optimize clinical outcomes.
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