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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
Published on: September 28, 2022
1Division of Endocrinology, Diabetes, and Metabolism, University of California, Los Angeles (UCLA) David Geffen School of Medicine, Los Angeles, California.
Cyclic Cushing syndrome, a rare condition, was effectively managed with osilodrostat. This medication demonstrated rapid, reversible inhibition of hypercortisolism, highlighting its potential for treating this challenging endocrine disorder.
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