Related Experiment Video
Updated: Feb 7, 2026

Isolation of Cellular Lipid Droplets: Two Purification Techniques Starting from Yeast Cells and Human Placentas
Published on: April 1, 2014
Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)
Yongchun Liang1, Xinbiao Fan1, Xiaofei Geng2
1Department of Cardiology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, P.R. China.
Abstract:
Diabetic cardiomyopathy (DCM) is a significant complication in patients with diabetes, but its pathogenesis is not fully understood. In recent years, dynamic regulation of lipid droplets (LDs) balance has gradually become a new therapeutic direction with great potential. LDs regulate lipid storage, energy supply and interconnected drivers; for instance, oxidative damage, inflammation, autophagy, ferroptosis, affect the function and cellular homeostasis of cardiomyocytes, macrophages and fibroblasts, and thus participate in DCM. The present review discusses the multiple functions of LDs in regulating DCM by affecting cell homeostasis and summarizes the research progress of therapies targeting LDs and related metabolic pathways, which may inform novel strategies for preventing and treating DCM.
Related Concept Videos
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipid Digestion
Storage
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Structure of Lipids

