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Long-Range Quantitative Multi-VOC Fluorescence Sensing Enabled by Donor-Carborane-Acceptor Assembly.
Zhaojin Wang1, Hui He1, Jiahui Li1
1Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province, Yancheng Institute of Technology, Yancheng 224051, China.
Analytical Chemistry
|February 6, 2026
Summary
New small molecule sensors offer quantitative fluorescence sensing for multiple volatile organic compounds (VOCs). The Cb-NA sensor demonstrates high sensitivity and discrimination for various VOCs, overcoming limitations of current technologies.
Area of Science:
- Materials Science
- Chemical Sensing
- Analytical Chemistry
Background:
- Developing single sensors for multiple volatile organic compounds (VOCs) using quantitative fluorescence (QF) is crucial.
- Existing polymer-based sensors face limitations, and small-molecule sensor development remains challenging.
Purpose of the Study:
- To develop novel small-molecule sensors with aggregation-induced emission and through-space charge transfer (TSCT) potential for multi-VOC sensing.
- To evaluate the performance of these sensors in detecting and discriminating various VOCs.
Main Methods:
- Synthesis of three donor-carborane-acceptor sensors (Cb-FL, Cb-NE, Cb-NA).
- Assembly of sensors into centrosymmetric dimers in crystals and aggregates in films.
- Testing film-based sensors for quantitative fluorescence (QF) response to multiple VOCs.
Main Results:
- Cb-NA film demonstrated an emission-off response to seven distinct analytes, including toluene and amines.
- QF sensitivity was maintained over three orders of magnitude (178 mg/m³-88.93 g/m³).
- Fast response/recovery times (16-60s/8-15s) and low detection limits (178-209 mg/m³) were achieved for Cb-NA.
Conclusions:
- Cb-NA sensor effectively utilizes TSCT in dissociated single molecules for independent emission quenching.
- This mechanism enables long-range QF sensitivity and discrimination of multiple VOCs.
- The developed small-molecule sensors show promise for advanced multi-VOC detection applications.
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