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Technology-Assisted Solutions to Enhance Auditory-Motor Synchronization During Walking in Progressive Multiple

Nele Vanbilsen1,2, Peter Feys1,2, Gianluca Florio1,2

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Summary
This summary is machine-generated.

Adaptive beat-alignment improved walking synchronization and gait dynamics in people with progressive multiple sclerosis (PwPMS). Dynamic balance and cognitive factors influenced synchronization performance during music-assisted walking.

Keywords:
adaptive algorithmbio-feedbackprogressive MSrehabilitationsensorimotor synchronization

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Area of Science:

  • Neurorehabilitation
  • Biomechanics
  • Human-Computer Interaction

Background:

  • Beat-based cues (music, metronomes) aid short-distance walking in people with progressive multiple sclerosis (PwPMS).
  • Prolonged walking assessment is crucial for real-world functional evaluation.
  • Adaptive beat-alignment algorithms' effects on PwPMS gait dynamics are unknown.

Purpose of the Study:

  • Investigate adaptive beat-alignment's impact on synchronization consistency and gait dynamics during prolonged walking in PwPMS.
  • Compare adaptive vs. non-adaptive beat-alignment with music and metronomes.
  • Examine cognitive and dynamic balance influences on synchronization.

Main Methods:

  • Healthy controls (HCs) and PwPMS completed 8-minute walks under five conditions: silence, music, and metronome, with or without adaptive beat alignment.
  • An algorithm adjusted phase and tempo in real-time to maintain baseline cadence.
  • Measured synchronization, gait parameters, dynamics, and clinical outcomes.

Main Results:

  • Adaptive beat-alignment enhanced synchronization consistency and gait dynamics compared to fixed-tempo cues.
  • Cognitive flexibility and working memory accounted for 6-10% of synchronization variance.
  • Dynamic balance significantly impaired synchronization (40%) across both adaptive and non-adaptive conditions.
  • Auditory cues led to slower walking and shorter strides than silence.

Conclusions:

  • Adaptive beat-alignment strategies are feasible for improving PwPMS synchronization consistency and gait dynamics.
  • Cognitive flexibility, working memory, and dynamic balance are key factors influencing synchronization performance in PwPMS.
  • Further research into adaptive cueing for gait rehabilitation in PwPMS is warranted.