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Updated: Feb 8, 2026

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
Published on: April 11, 2012
Utility of Animal Models of Pneumonia and Sepsis
Hiroki Taenaka1, Mazharul Maishan2, Ruriko Watanabe3
1Cardiovascular Research Institute, University of California, San Francisco, CA, USA; Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Abstract:
Pneumonia remains a leading cause of mortality worldwide. While infectious diseases pose a greater burden in resource-limited regions, pneumonia has the highest incidence and mortality rates among all infectious diseases globally. In the United States, mortality rates due to pneumonia and influenza have shown little improvement over the past 50 years. Sepsis also remains a major global health challenge, with a high incidence and a mortality rate of approximately 20%. Despite significant advancements in medical science, progress in identifying effective therapeutic strategies has been slow.
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