Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Characteristics and Nomenclature of Copolymers01:24

Characteristics and Nomenclature of Copolymers

3.4K
Copolymers are the products obtained from the polymerization of multiple monomer species. So, in a polymer chain itself, there can be multiple repeating units that come from different monomers. The process of synthesizing a polymer from different monomer species is called copolymerization. When two monomers are involved, the polymer is known as a bipolymer. Polymers with three and four monomers are termed terpolymers and quaterpolymers, respectively. Figure 1 depicts the copolymerization of...
3.4K
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene01:13

Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene

7.5K
Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.
7.5K
Separation of Sister Chromatids02:17

Separation of Sister Chromatids

4.5K
At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
4.5K
Separable Differential Equations01:20

Separable Differential Equations

107
A separable differential equation is a type of first-order differential equation where the derivative dy/dx can be expressed as a product of two functions: one that depends only on x and another that depends only on y. This allows for the rearrangement of the equation so that all terms involving y are on one side, and all terms involving x are on the other. This process, known as the separation of variables, simplifies the process of solving the equation by enabling the integration of both...
107
Optimizing Chromatographic Separations01:15

Optimizing Chromatographic Separations

1.0K
Optimizing chromatographic separations is crucial for obtaining clean separations in a minimum amount of time. Optimization is required for several factors, including kinetic effects related to band broadening, plate height, capacity factor, and separation factor.
Band broadening refers to spreading solute bands as they travel through the column. This broadening can impact resolution. Plate height (H) represents the length required for one theoretical plate. A lower plate height corresponds to...
1.0K
Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

7.6K
Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sparingly PEGylated Adipate Copolymers via Enzymatic Synthesis as Nano-Carriers for Solid Dispersions.

Biomacromolecules·2026
Same author

Concurrently coupling particle and continuum simulations to study block copolymer membrane fabrication.

The Journal of chemical physics·2026
Same author

Impact of Small-Alkane Solvents on Polyolefin Hydrogenolysis over a Ruthenium Catalyst.

Industrial & engineering chemistry research·2026
Same author

Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide.

Science (New York, N.Y.)·2026
Same author

Tuning Anion Composition and Mobility to Balance Ionic Conductivity and Cation Selectivity in Solid Polymer Electrolytes.

Macromolecules·2026
Same author

Corrigendum to "Directed evolution of an integral membrane monooxygenase unlocks its full potential" [Bioresour. Technol. 447 (2026) 134249].

Bioresource technology·2026

Related Experiment Video

Updated: Feb 10, 2026

Gyroid Nickel Nanostructures from Diblock Copolymer Supramolecules
08:40

Gyroid Nickel Nanostructures from Diblock Copolymer Supramolecules

Published on: April 28, 2014

12.9K

Exploring Microphase Separation in Semi-Fluorinated Diblock Copolymers: A Combined Experimental and Modeling

Mona Semsarilar1, Martin J Greenall2, Alex H Balzer3,4

  • 1Institut Européen des Membranes (IEM), CNRS, ENSCM, Univ Montpellier, Montpellier 34090, France.

ACS Polymers Au
|February 9, 2026
PubMed
Summary

This study explores polystyrene-block-poly(pentafluorostyrene) diblock copolymers, revealing a transition from coil-coil to rod-coil behavior driven by block length, not just chemical differences. This highlights strong self-assembly in similar polymer blocks.

Keywords:
X-ray reflectometryX-ray scatteringblock copolymersself-assemblystrong segregation theory

More Related Videos

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.6K
Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

8.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

Gyroid Nickel Nanostructures from Diblock Copolymer Supramolecules
08:40

Gyroid Nickel Nanostructures from Diblock Copolymer Supramolecules

Published on: April 28, 2014

12.9K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.6K
Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp
09:58

Investigating the Three-dimensional Flow Separation Induced by a Model Vocal Fold Polyp

Published on: February 3, 2014

8.9K

Area of Science:

  • Polymer Science
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Block copolymers self-assemble into nanoscale morphologies, crucial for advanced materials.
  • Polystyrene-block-poly(pentafluorostyrene) offers a model system for studying self-assembly due to high antagonism between blocks.
  • Understanding the influence of block length and inherent chain stiffness on self-assembly is key.

Purpose of the Study:

  • To investigate the bulk self-assembly behavior of polystyrene-block-poly(pentafluorostyrene) diblock copolymers.
  • To explore the transition from coil-coil to rod-coil segregation behavior.
  • To construct an experimental phase diagram and validate theoretical models.

Main Methods:

  • Synthesis of 41 diblock copolymer samples using reversible addition-fragmentation chain transfer (RAFT) polymerization.
  • Characterization of molecular weight distribution and dispersity (D).
  • Analysis of nanoscale morphologies via small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) after thermal annealing.

Main Results:

  • Well-defined nanoscale morphologies were observed, dependent on molecular composition.
  • An experimental phase diagram was constructed, with a Flory-Huggins interaction parameter (χ) estimated at 0.2.
  • A transition from coil-coil to rod-coil behavior was observed by reducing the length of the stiffer fluorinated block, without altering temperature or chemical composition.

Conclusions:

  • The study demonstrates strong microphase separation in AB diblock copolymers with relatively similar chemical units.
  • A transition from rod-coil to coil-coil segregation behavior can be achieved by tuning block length.
  • This work provides insights into controlling self-assembly through manipulation of block stiffness and length.