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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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[3 + 2] Cycloadditions of Tertiary Amine N‑Oxides and Azoarenes as a Route to Substituted 1,2,4-Triazolidines

Nicholas A Frankos1, Malavika S Nair1, Aiden M Lane1

  • 1Department of Chemistry and Biochemistry, Duquesne University, 600 Forbes Ave. Pittsburgh, Pennsylvania 15282, United States.

ACS Organic & Inorganic Au
|February 9, 2026
PubMed

Keywords:
1,2,4-triazolidineantibacterialazoarenecycloadditiontertiary amine N-oxide

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