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An Axially Chiral Pyridyno-allenophane in a 2:1 Edge-to-Face Silver(I) Sandwich Complex: Synthesis and Structural
Jonathan Álvarez-García1, María Magdalena Cid2
1Departamento de Química Orgánica, Ciencias Experimentais, Universidade de Vigo, Vigo E-36310, Spain.
Abstract:
We synthesized and characterized silver-(I) complexes featuring chiral pyridyno-allenophanesa class of cyclophanes integrating pyridine, alkyne, and allene units within a macrocyclic framework. X-ray diffraction revealed a 1:1 (ligand:metal) complex stabilized by a rare N···Ag···OH2···N bridging motif, and a 2:1 asymmetric sandwich-type complex, representing one of the few structurally characterized examples of its kind. Complementary solution studies (ECD, NMR, and HRMS) confirmed the persistence and stability of the 1:1 complex, which exhibits pronounced chiroptical activity. These findings establish pyridyno-allenophanes as versatile, robust scaffolds for constructing dynamic, chiral metal complexes with promising potential in supramolecular chemistry.
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