Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

1.1K
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
1.1K
Opioid Receptors: Overview01:22

Opioid Receptors: Overview

4.5K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
4.5K
Student t Distribution01:31

Student t Distribution

14.2K
The population standard deviation is rarely known in many day-to-day examples of statistics. When the sample sizes are large, it is easy to estimate the population standard deviation using a confidence interval, which provides results close enough to the original value. However, statisticians ran into problems when the sample size was small. A small sample size caused inaccuracies in the confidence interval.
The Student t distribution was developed by William S. Goset (1876–1937) of the...
14.2K
Microsoft Excel: Student's t-Test01:25

Microsoft Excel: Student's t-Test

1.7K
Student's t-test in Microsoft Excel is a statistical method used to compare the means of two groups to determine if they are significantly different from each other. It's commonly used to evaluate hypotheses, such as testing whether a treatment has an effect compared to a control group. Excel provides built-in functions to perform t-tests, making it accessible for users needing to conduct basic statistical analysis.
To conduct a t-test in Excel, use the T.TEST function or the "Data...
1.7K
Comparing Experimental Results: Student's t-Test01:09

Comparing Experimental Results: Student's t-Test

6.1K
The t-test is a statistical method used to compare the sample mean with a population mean or compare two means from two data sets. The test statistic is calculated from the standard deviation, mean, and number of measurements in the data set at a selected confidence interval and then compared to a table of critical values at this confidence level. If the test statistic is smaller than the critical value, the null hypothesis is accepted. In this case, we state that the difference between the...
6.1K
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

1.0K
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Theranostic strategies in prostate cancer: Advances in PSMA PET imaging and radioligand therapy.

Cancer treatment and research communications·2026
Same author

Deep generative modeling of sample-level heterogeneity in single-cell genomics.

Nature methods·2025
Same author

Scvi-hub: an actionable repository for model-driven single-cell analysis.

Nature methods·2025
Same author

Case Report: Refractory Ventricular Fibrillation Resolved by Double External Defibrillation and Beta Blockade.

Clinical practice and cases in emergency medicine·2025
Same author

Connect Care Project, Bridging the Gap Between Acute and Post-Acute Care.

Journal of general internal medicine·2025
Same author

Selection Over Small and Large Spatial Scales in the Face of High Gene Flow.

Molecular ecology·2025

Related Experiment Video

Updated: Feb 10, 2026

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

13.2K

Opioid Overdose Simulation in Medical Student Education.

James Mangano1, Matthew J Sarsfield1, Hannah Charland1

  • 1SUNY Upstate Medical University, Department of Emergency Medicine, Syracuse, NY.

Journal of Education & Teaching in Emergency Medicine
|February 9, 2026
PubMed
Summary
This summary is machine-generated.

High-fidelity simulation training significantly boosted medical students' confidence and knowledge in recognizing and treating opioid overdoses. This approach effectively prepares future emergency physicians to manage overdose emergencies, including Naloxone administration.

More Related Videos

Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research
07:05

Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research

Published on: January 16, 2026

622
Mixed Reality for Education MRE Implementation and Results in Online Classes for Engineering
04:12

Mixed Reality for Education MRE Implementation and Results in Online Classes for Engineering

Published on: June 23, 2023

1.1K

Related Experiment Videos

Last Updated: Feb 10, 2026

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
11:32

A Neuroscientific Approach to the Examination of Concussions in Student-Athletes

Published on: December 8, 2014

13.2K
Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research
07:05

Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research

Published on: January 16, 2026

622
Mixed Reality for Education MRE Implementation and Results in Online Classes for Engineering
04:12

Mixed Reality for Education MRE Implementation and Results in Online Classes for Engineering

Published on: June 23, 2023

1.1K

Area of Science:

  • Medical Education
  • Emergency Medicine
  • Toxicology

Background:

  • The opioid epidemic has drastically increased opioid overdose cases and deaths, making emergency departments a critical frontline for intervention.
  • Rapid recognition and timely Naloxone administration are vital for saving lives during opioid overdoses.

Purpose of the Study:

  • To evaluate the effectiveness of a high-fidelity simulation in enhancing third-year medical students' ability to recognize and manage opioid overdoses.
  • To assess improvements in students' confidence and knowledge regarding opioid overdose treatment, including Naloxone administration.

Main Methods:

  • A high-fidelity simulation scenario of an opioid overdose was integrated into an emergency medicine clerkship.
  • Medical students participated in the simulation, practicing recognition and treatment of opioid overdose.
  • Pre- and post-simulation surveys using 5-point Likert scales measured changes in learners' confidence and perceived competence.

Main Results:

  • The simulation led to significant improvements in learners' confidence and knowledge across all assessed domains.
  • Post-simulation surveys indicated marked gains in the ability to recognize, manage, and treat opioid overdoses.
  • Students demonstrated increased competence in administering Naloxone and performing basic life support interventions.

Conclusions:

  • High-fidelity simulation is a highly effective educational tool for teaching critical emergency medicine skills related to opioid overdose.
  • The simulation successfully prepared medical students to manage opioid overdose cases with increased confidence and competence.
  • This training approach has the potential to reduce opioid-related mortality by equipping future healthcare providers with essential skills.