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Published on: March 12, 2019
Wilkie's Syndrome: Laparoscopic Duodenojejunostomy
Magdalena Bozzetti1, Benjamin Romei1, Juliana Leszczynski1
1Gastrointestinal Surgery Division, Hospital Nacional Prof. A. Posadas, Buenos Aires, Argentina.
Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
|February 9, 2026
Summary
Superior mesenteric artery syndrome (SMAS) is a rare condition causing duodenal compression. Laparoscopic duodenojejunostomy offers a minimally invasive surgical solution for patients unresponsive to conservative treatment.
Area of Science:
- Gastroenterology
- Surgical Case Reports
Background:
- Superior mesenteric artery syndrome (SMAS) is a rare condition characterized by duodenal compression between the aorta and superior mesenteric artery, often due to a narrow aortomesenteric angle (<25°).
- Clinical presentation includes chronic abdominal pain, vomiting, early satiety, and weight loss, predominantly affecting young women.
- Diagnosis is typically confirmed via imaging, with computed tomography being a primary tool.
Purpose of the Study:
- To present a case of SMAS in a young patient with an eating disorder.
- To highlight the diagnostic and therapeutic challenges of SMAS.
- To emphasize the efficacy of laparoscopic duodenojejunostomy as a surgical intervention.
Main Methods:
- A 20-year-old female patient with a history of eating disorder presented with symptoms consistent with SMAS.
- Computed tomography confirmed a significantly reduced aortomesenteric angle (15°) and distance (4 mm).
- Following failure of conservative management, the patient underwent a laparoscopic duodenojejunostomy.
Main Results:
- The patient experienced excellent postoperative outcomes.
- Hospital discharge was achieved on postoperative day 5.
- Laparoscopic duodenojejunostomy proved to be a reliable and minimally invasive solution.
Conclusions:
- SMAS presents diagnostic and therapeutic challenges due to its rarity and nonspecific symptoms.
- Nutritional rehabilitation is the cornerstone of initial management.
- Laparoscopic duodenojejunostomy is the preferred surgical option for refractory cases.

