Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

1.1K
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
1.1K
Cancer Therapies02:49

Cancer Therapies

10.2K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.2K
Types of Hormones02:13

Types of Hormones

84.1K
Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
84.1K
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

232
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
232
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.0K
Hormonal Regulation01:33

Hormonal Regulation

36.2K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
36.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physical and mental health impact of perimenopause, menopause and post menopause in a diverse global population (MARIE Project- Global Chapter WP 2a): cross-sectional quantitative data from a mixed-methods study.

EClinicalMedicine·2026
Same author

Menopause in Brazil: lived experiences, inequities, and opportunities for inclusive care (MARIE-Brazil WP2a).

Women & health·2026
Same author

Women and psychosis: a guide to evidence-based, hormone-informed care.

The lancet. Psychiatry·2026
Same author

Comparative Efficacy of Elinzanetant Versus Other Non-Hormonal Pharmaceutical Therapies for the Treatment of Moderate-to-Severe Vasomotor Symptoms Associated With Menopause: A Network Meta-Analysis.

BJOG : an international journal of obstetrics and gynaecology·2026
Same author

Breaking the silence and building strength; rethinking menopause care through exercise and cultural insight.

Frontiers in global women's health·2026
Same author

Navigating menopausal health in Oman (Marie Oman WP2a).

Scientific reports·2026
Same journal

Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time-Trend Study.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

Long-Term Outcomes After Retropubic and Transobturator Sling Procedures: Reoperation for Recurrent Stress Urinary Incontinence.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

First Trimester Screening for Preterm Preeclampsia in the United Kingdom: A Cost-Effectiveness Analysis.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

Correction to "The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-Top Guideline No. 69)".

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

Large Language Models on European Guidelines for Cervical Cancer: Implications of Design and Clinical Applicability.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

Internal Consistency of the Hadlock Estimated Fetal Weight Reference: Methodological Analysis.

BJOG : an international journal of obstetrics and gynaecology·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.6K

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review.

Gabriella Yongue1,2, Zachary Nash2,3, Vikram Talaulikar2,3

  • 1University College London Cancer Institute, London, UK.

BJOG : an International Journal of Obstetrics and Gynaecology
|February 9, 2026
PubMed
Summary
This summary is machine-generated.

Hormone replacement therapy (HRT) is effective for menopausal symptoms and bone health, but past cancer concerns persist. This review clarifies HRT risks and benefits for informed patient decisions, especially for cancer survivors.

Keywords:
BRCA mutationHRTcancer menopausehormone replacement therapymenopauseoestrogenprogesteronerisk‐reducing oophorectomy

More Related Videos

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

30.3K
Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
08:45

Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring

Published on: November 13, 2012

14.3K

Related Experiment Videos

Last Updated: Feb 11, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.6K
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

30.3K
Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
08:45

Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring

Published on: November 13, 2012

14.3K

Area of Science:

  • Reproductive Endocrinology
  • Oncology
  • Women's Health

Background:

  • Hormone replacement therapy (HRT) is a primary treatment for menopausal symptoms and osteoporosis prevention.
  • Past studies linking HRT to increased cancer risk created controversy, impacting clinical practice and patient perception.
  • Cancer survivors or those with genetic risks face heightened concerns regarding HRT use due to potential cancer promotion.

Purpose of the Study:

  • To comprehensively review the evidence on the safety and efficacy of HRT.
  • To provide clinicians with an overview to guide patient discussions on HRT risks and benefits.
  • To promote shared, informed decision-making regarding HRT in diverse patient populations, including cancer survivors.

Main Methods:

  • Literature review of existing studies on HRT, menopausal symptoms, cancer risk, and survivorship.
  • Analysis of evidence regarding the relative safety of HRT in various contexts.
  • Synthesis of information to create a clinical overview for patient counseling.

Main Results:

  • HRT effectively manages vasomotor and genitourinary symptoms of menopause.
  • HRT offers significant benefits in mitigating long-term risks like osteoporosis.
  • Despite past controversies, current evidence suggests a nuanced understanding of HRT safety, particularly when considering individual risk factors.

Conclusions:

  • HRT remains a cornerstone for menopausal symptom management and bone health.
  • Addressing patient and clinician concerns regarding cancer risk is crucial for appropriate HRT utilization.
  • Informed decision-making, considering both risks and benefits, is essential for optimizing quality of life in menopausal women, including cancer survivors.