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Noninvasive, High-throughput Determination of Sleep Duration in Rodents
Published on: April 18, 2018
Sleep Duration and Chronic Kidney Disease Among Older US Adults
Shirmila Syamala1, Unnikrishnan Pillai2, Nasseer A Masoodi3
1Department of Geriatrics and Long-Term Care, Hamad Medical Corporation, Doha, Qatar (SS).
Abstract:
Chronic kidney disease (CKD) is a major public health problem and the prevalence of CKD is substantially higher in older adults. Similarly insufficient sleep and abnormal sleep duration is more common among older adults. However, the relation between sleep duration and CKD has not been widely examined in older adults. We examined the association between long and short sleep duration and CKD in a large, multiethnic sample of older US adults aged ≥60 years (N = 178 268) who participated in the 2022 Behavioral Risk Factor Surveillance System. Sleep duration was categorized into 5 groups: ≤5, 6, 7, 8, and ≥9 h. Main outcome-of-interest was CKD (prevalence = 7.3%). We found both short and long sleep duration to be associated with higher prevalence of CKD. Compared to 7 hours of sleep (referent), the multivariable-adjusted odds ratio (95% confidence interval) of CKD was 1.32 (1.16-1.51) for 6 h of sleep, 1.55 (1.33-1.81) for ≤5 h of sleep, 1.27 (1.12-1.43) for 8 h of sleep, and 1.41 (1.23-1.62) for ≥9 h of sleep. The association was consistently present in subgroup analyses by gender, age, race/ethnicity, and body mass index. In conclusion, both short and long sleep durations are associated with CKD in older adults.
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