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UCell and pyUCell: single-cell gene signature scoring for R and Python.

Massimo Andreatta1,2,3,4, Santiago J Carmona1,2,3,4

  • 1Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva 1206, Switzerland.

Bioinformatics (Oxford, England)
|February 10, 2026
PubMed
Summary

Gene signature scoring quantifies biological signals in single-cell omics data. UCell (R) and pyUCell (Python) provide fast, robust tools for this analysis, integrating with major platforms.

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