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Comparison study between stereotactic versus digital breast tomosynthesis-guided core needle biopsy
Xiaozheng Guo1, Guang Yang1, Yanan Li1
1Department of Radiology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Background:
Digital breast tomosynthesis (DBT)-guided biopsy has provided a direct method for the suspicious breast abnormalities detected by DBT. The aim of this study was to assess performance and outcomes of stereotactic (ST) and DBT-guided core needle biopsy (CNB).
Methods:
All CNBs from August 2021 to July 2024 at our institution were retrospectively reviewed. The number of image exposures obtained, average glandular dose (AGD) per overall procedure, AGD per acquisition, procedure time and pathologic results of CNB, pathologic results of surgical excision when available, and different B categories of concordant or upgrade rate were recorded. Mann-Whitney U test or two independent-sample t-test were used to compare continuous variables and Chi-squared test or Fisher's exact test for categorical variables. If data were non-normal distributions, represented by median [1st quartile-3rd quartile (Q1-Q3)].
Results:
A total of 134 lesions used DBT-guided CNB, and 100 used ST-guidance. The number of image exposures was lower for DBT-guided (1 [1-2] images) than for ST-guided (3 [3-3] images) CNB (P<0.001). The AGD overall procedure for ST-guided was 7.39 (6.23-8.09) vs. 2.09 (1.75-2.98) mGy for DBT (P<0.001). The AGD per acquisition was lower for DBT-guided than for ST-guided (1.89 [1.56-2.09] vs. 2.43 [2.10-2.72] mGy) CNB (P<0.001). In DBT-guided CNB, the procedure time was significantly reduced (571.0 [484.0-716.5] vs. 827.0 [712.5-968.5] s) (P<0.001). There were no significant differences between ST-guided and DBT-guided CNB in different B categories of the concordant or upgrade rate (all P>0.05).
Conclusions:
Reduced procedure time and fewer image exposures were achieved with DBT-guided CNB, with overall less AGD, compared to ST-guided CNB.
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