Contrast-enhanced mammography-guided biopsy and localization: initial outcome and a single institution's experience

Area of Science:

• Radiology
• Oncology
• Medical Imaging

Background:

• Contrast-enhanced mammography (CEM) offers high sensitivity for detecting breast lesions, including those not visible on conventional imaging.
• CEM-guided vacuum-assisted biopsy (VAB) is established, but data on CEM-guided core needle biopsy (CNB) and wire localization (WL) are lacking.

Purpose of the Study:

• To evaluate the initial outcomes of CEM-guided CNB and WL for breast enhancing lesions.
• To assess the feasibility, success rates, and complication profiles of these CEM-guided biopsy techniques.

Main Methods:

• Retrospective analysis of 35 lesions in 35 patients undergoing CEM-guided CNB or WL.
• Data collected included patient and lesion characteristics, procedural details, pathology, and complications.
• Procedures were performed using a vertical approach.

Main Results:

• 100% success rate for CEM-guided procedures with only 5.7% minor complications (hematomas).
• Mean lesion size was 2.1 cm; 48.6% were masses and 51.4% were non-mass enhancements (NME).
• CEM-guided CNB (24 lesions) had a mean procedure time of 14.2 min; CEM-guided WL (11 lesions) had a mean procedure time of 12.4 min.

Conclusions:

• CEM-guided CNB and WL are promising techniques for enhancing breast lesions.
• These procedures demonstrate high success rates, short operation times, and low complication rates.
• Further validation with larger sample sizes is needed to confirm these preliminary findings.