Related Experiment Video

Updated: Feb 13, 2026

Electrophoretic Delivery of γ-aminobutyric Acid GABA into Epileptic Focus Prevents Seizures in Mice
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Published on: May 16, 2019

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Stathmin 1 regulates epileptic seizures by influencing GABAA R-mediated inhibitory synaptic activity

Min Yang1, Yida Hu1, Junhong Wu1

  • 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, 1 Youyi Road, Chongqing 400016, China.

Neurobiology of Disease
|February 11, 2026
PubMed
Summary

Stathmin 1 (STMN1) influences epilepsy by affecting inhibitory neuron function and GABAA receptors. Downregulating STMN1 reduces seizure susceptibility, suggesting it as a therapeutic target for epilepsy treatment.

Keywords:
EpilepsyGABAA receptorInhibitory synaptic transmissionMicrotubulestathmin1

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