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Updated: Feb 13, 2026

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Assessing Insulin Resistance: The Triglyceride-Glucose (TyG) Index and Its Variants
None:
The predictive value in determining a person's insulin resistance (IR) is relevant for underwriters and medical directors of life and disability insurance companies as these measurements may screen for the future development of prediabetes and type 2 diabetes, metabolic dysfunction diseases, and cardiovascular disease morbidity and mortality. This treatise is a review of the importance of early recognition of IR by the routine measurements of the triglyceride-glucose (TyG) index and its variants. A review of PubMed for relevant articles reveals that most large studies have been done in Asian populations, suggesting that these measurements may not have gained sufficient attention in the U.S. and European disability and life insurance markets.
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