Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

475
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
475
Social Anxiety Disorder01:28

Social Anxiety Disorder

551
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
551
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

752
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
752
Control System Problem01:21

Control System Problem

443
In an open-loop system, such as a basic thermostat, the poles of the transfer function influence the system's response but do not determine its stability. However, when feedback is introduced to form a closed-loop system, such as an advanced thermostat that adjusts heating based on room temperature, stability is governed by the new poles of the closed-loop transfer function.
When forming a closed-loop system, issues can arise if the poles cross into the unstable region, leading to potential...
443
Combinatorial Gene Control02:33

Combinatorial Gene Control

9.7K
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
9.7K
Control Systems01:10

Control Systems

1.9K
Control systems are everywhere in contemporary society, influencing diverse applications from aerospace to automated manufacturing. These systems can be found naturally within biological processes, such as blood sugar regulation and heart rate adjustment in response to stress, as well as in man-made systems like elevators and automated vehicles. A control system is essentially a network of subsystems and processes that collaboratively convert specific inputs into desired outputs.
At the heart...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and clinical validation of the short version of the NIMHANS-NMHS-2 disability scale.

Indian journal of psychiatry·2026
Same author

Dynamic network reconfigurations during task engagement following resting state in adolescent onset schizophrenia.

bioRxiv : the preprint server for biology·2026
Same author

Minimally Guided App-Based Intervention for Nontreatment-Seeking Psychologically Distressed Adults: Protocol for a Randomized Controlled Trial.

JMIR research protocols·2026
Same author

Resting-state functional connectivity alterations in obsessive-compulsive disorder: relationships between connectivity and clinical profiles in the Global OCD study.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2026
Same author

Strengthening Community-based Preventive Psychiatry-related Interventional Research in India by Employing SWOT Analysis.

Indian journal of psychological medicine·2026
Same author

Early adversity links more to transdiagnostic than obsessive-compulsive disorder (OCD)-specific features: Findings from a large multinational study.

Comprehensive psychiatry·2026
Same journal

Predicting Chemotherapy Response from Staging Laparoscopy Images.

medRxiv : the preprint server for health sciences·2026
Same journal

Development and External Validation of a Machine Learning Model for 10-Year Ischemic Stroke Risk Prediction in Diverse Populations.

medRxiv : the preprint server for health sciences·2026
Same journal

MCH-Guard: Multimodal Machine Learning Framework for Risk Stratification of Cerebral Microhemorrhage Risk in the Alzheimer's Disease Neuroimaging Initiative.

medRxiv : the preprint server for health sciences·2026
Same journal

Genetic and maternal environmental contributions to estimated fetal weight at 20 weeks gestation compared with birthweight.

medRxiv : the preprint server for health sciences·2026
Same journal

Better immediate declarative memory is associated with forgetting during locomotor adaptation in chronic stroke and in older adults.

medRxiv : the preprint server for health sciences·2026
Same journal

An empirical Bayes framework for burden and dispersion association tests helps prioritize rare variants associated with Alzheimer's disease.

medRxiv : the preprint server for health sciences·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments
09:43

A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments

Published on: April 15, 2014

11.1K

Smartphone app-based Integrated Cognitive Control Training for Anxiety Disorders: Study protocol for a Multi-site

Himani Kashyap, Snehil Gupta, Haroon Lone

    Medrxiv : the Preprint Server for Health Sciences
    |February 12, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This study tests Integrated Cognitive Control Training (ICCT) for anxiety disorders, using a smartphone app to improve cognitive function and reduce symptoms. Findings will assess the feasibility and scalability of this digital intervention for anxiety.

    More Related Videos

    Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
    03:26

    Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

    Published on: March 8, 2024

    3.6K
    Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
    08:53

    Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

    Published on: June 6, 2025

    1.8K

    Related Experiment Videos

    Last Updated: Feb 13, 2026

    A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments
    09:43

    A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments

    Published on: April 15, 2014

    11.1K
    Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
    03:26

    Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain

    Published on: March 8, 2024

    3.6K
    Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
    08:53

    Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

    Published on: June 6, 2025

    1.8K

    Area of Science:

    • Neuroscience
    • Clinical Psychology
    • Digital Health

    Background:

    • Anxiety disorders (ADs) are linked to cognitive deficits, impairing clinical and socio-occupational functioning.
    • Targeted interventions are crucial for managing cognitive dysfunction in ADs.

    Purpose of the Study:

    • To evaluate the efficacy of Integrated Cognitive Control Training (ICCT) in adults with ADs through a multi-site randomized controlled trial (RCT).
    • To assess ICCT's impact on cognitive functions, anxiety symptoms, and neural circuits of cognitive control.
    • To determine the feasibility and scalability of a smartphone-delivered ICCT program for ADs.

    Main Methods:

    • A multi-site RCT involving 100 adults diagnosed with ADs, randomized to ICCT or Treatment As Usual (TAU).
    • ICCT delivered via weekly therapist-guided sessions and a smartphone app (Cogtrain) for homework.
    • Multimodal assessments including clinical scales (Hamilton Anxiety Rating Scale), neuropsychological tests, and fMRI at multiple time points.

    Main Results:

    • Expected to demonstrate enhancement in cognitive functioning and reduction in anxiety symptoms following ICCT.
    • Anticipated changes in the neural circuits of cognitive control, as evidenced by fMRI.
    • Feasibility and acceptance metrics will be recorded to inform intervention scalability.

    Conclusions:

    • ICCT shows potential as an effective intervention for improving cognitive and overall functioning in adults with ADs.
    • Smartphone-delivered ICCT offers a scalable and cost-effective approach, particularly for resource-constrained settings.
    • This study protocol outlines a rigorous evaluation of a novel digital intervention for anxiety disorders.