Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

To pulse or not to pulse.

C Mavroudis

    The Annals of Thoracic Surgery
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Pulsatile blood flow enhances kidney function, lymph flow, and oxygen consumption compared to nonpulsatile flow during cardiopulmonary bypass (CPB). This improved perfusion may be due to vascular shocks, increased lymph movement, and better vascular patency.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The cost of cytoreductive surgery and perioperative intraperitoneal chemotherapy in the treatment of peritoneal malignancy in one Greek institute.

    Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2013
    Same author

    An improved in vivo method for atrioventricular node ablation via thoracotomy.

    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2010
    Same author

    Arrhythmia management in the Fontan patient.

    Pediatric cardiology·2007
    Same author

    Cardiac plasma cell granulomas: response to oral steroid treatment.

    Pediatric cardiology·2004
    Same author

    Alterations in the natriuretic hormone system related to cardiopulmonary bypass in infants with congestive heart failure.

    Pediatric cardiology·2004
    Same author

    Long-term survival of aortic atresia following biventricular corrective surgery.

    Pediatric cardiology·2002
    Same journal

    Coronary artery bypass grafting based on computed tomography-derived fractional flow reserve versus angiography: Early results.

    The Annals of thoracic surgery·2026
    Same journal

    Beyond R0: Margin Cytology and Local Control After Sublobar Resection.

    The Annals of thoracic surgery·2026
    Same journal

    Deferred AVR During CABG in Moderate Aortic Stenosis: Lower Index Risk or Deferred Cumulative Risk?

    The Annals of thoracic surgery·2026
    Same journal

    The Renaissance of Transapical TAVR: From Competing Access Route to Enabling Platform for Hybrid Heart Therapy.

    The Annals of thoracic surgery·2026
    Same journal

    A Moving Target: Interpreting Post-TAVI Reintervention in a Rapidly Evolving Era.

    The Annals of thoracic surgery·2026
    Same journal

    False Lumen Remodeling Versus Intraluminal Graft Thrombosis: Distinct Phenomena After Frozen Elephant Trunk Repair.

    The Annals of thoracic surgery·2026
    See all related articles

    Area of Science:

    • Cardiovascular physiology
    • Biomedical engineering

    Background:

    • Pulsatile and nonpulsatile blood flow are critical in cardiopulmonary bypass (CPB), organ perfusion, and myocardial preservation.
    • While early research was divided, recent studies indicate advantages of pulsatile flow.

    Purpose of the Study:

    • To review the benefits of pulsatile flow over nonpulsatile flow in various medical applications.
    • To explore the physiological mechanisms underlying the superiority of pulsatile perfusion.
    • To discuss novel methods for generating pulsatile flow.

    Main Methods:

    • Literature review comparing pulsatile and nonpulsatile blood flow studies.
    • Analysis of physiological parameters affected by different flow types.
    • Discussion of theoretical explanations for pulsatile flow's efficacy.

    Related Experiment Videos

    Main Results:

    • Pulsatile perfusion improves kidney function, lymph flow, and oxygen consumption.
    • Nonpulsatile CPB can lead to increased total peripheral resistance and mean arterial pressure.
    • Proposed mechanisms include "vascular shocks," enhanced interstitial fluid diffusion, increased lymph movement, and maintained vascular patency.

    Conclusions:

    • Pulsatile blood flow offers significant physiological benefits over nonpulsatile flow.
    • Understanding these benefits is crucial for optimizing CPB and organ perfusion strategies.
    • Advancements in generating pulsatile flow are being adapted for clinical use.