Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.1K
VSEPR Theory for Determination of Electron Pair Geometries
46.1K
What is Genetic Engineering?00:49

What is Genetic Engineering?

80.4K
Overview
80.4K
Reaction Mechanisms03:06

Reaction Mechanisms

31.2K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
31.2K
Prediction Intervals01:03

Prediction Intervals

3.4K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
3.4K
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

1
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
1
Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

1.4K
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Personalized Pathogenic Nanoplastic Coronas Orchestrate Efferocytosis-Driven Immune Evasion in Lung Adenocarcinoma.

ACS nano·2026
Same author

Reassessing Toxicity Claims of Micro- and Nanoplastics in Human Health Research.

Environment & health (Washington, D.C.)·2026
Same author

Elucidation of the Structure Determinants for the Delivery Process of Phospholipid-Based Nanomaterials Using a Combinatorial Nanoparticle Library Approach.

ACS applied materials & interfaces·2026
Same author

Navigating the Endothelial Barrier: A Multiscale Framework for Precision Nanomedicine.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Predicting Nanotoxicity across Materials Using Interpretable Machine Learning and Descriptors Based on the Periodic Table.

ACS applied materials & interfaces·2025
Same author

Nanoplastics Toxicity Is a Subset of Nanotoxicology, Not a Separate Field.

Environment & health (Washington, D.C.)·2025

Related Experiment Video

Updated: Feb 13, 2026

Kupffer Cell Isolation for Nanoparticle Toxicity Testing
09:49

Kupffer Cell Isolation for Nanoparticle Toxicity Testing

Published on: August 18, 2015

24.7K

Predictive and Mechanism-Based Toxicity Evaluation of Engineered Nanoparticles.

Rongrong Liu1, Bing Yan1

  • 1Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Institute of Environmental Research at the Greater Bay Area, Ministry of Education, Guangzhou University, Guangzhou 510006, China.

Nanomaterials (Basel, Switzerland)
|February 12, 2026
PubMed
Summary

Engineered nanomaterials are increasingly used across various sectors. This study explores their expanding applications and implications.

Area of Science:

  • Nanotechnology and Materials Science

Background:

  • The proliferation of nanotechnology has led to extensive use of engineered nanomaterials.
  • These materials are integral to advancements in energy, electronics, medicine, and consumer goods.

More Related Videos

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
08:51

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry

Published on: March 1, 2013

16.7K
Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
06:42

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance

Published on: September 27, 2024

2.9K

Related Experiment Videos

Last Updated: Feb 13, 2026

Kupffer Cell Isolation for Nanoparticle Toxicity Testing
09:49

Kupffer Cell Isolation for Nanoparticle Toxicity Testing

Published on: August 18, 2015

24.7K
Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
08:51

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry

Published on: March 1, 2013

16.7K
Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
06:42

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance

Published on: September 27, 2024

2.9K