Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

1.2K
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
1.2K
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

931
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
931
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

383
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
383
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.6K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.6K
GIS Software, Hardware, and Sources of GIS Data01:23

GIS Software, Hardware, and Sources of GIS Data

825
A Geographic Information System (GIS) combines specialized software and hardware to effectively manage, analyze, and present spatial and related data. GIS software includes critical functionalities such as a user interface for easy navigation, database management tools for handling spatial and attribute data, and data retrieval features for efficient access. Analytical tools transform raw data into insights, while display functions produce maps and reports in various formats for effective...
825
SN1 Reaction: Stereochemistry02:15

SN1 Reaction: Stereochemistry

10.5K
This lesson provides an in-depth discussion of the stereochemical outcomes in an SN1 reaction.
In the first step of an SN1 reaction, the bond between the electrophilic carbon and the leaving group ionizes to generate the carbocation intermediate. The second step of the mechanism is the nucleophilic attack.
In the formed carbocation, the positively charged carbon is sp2 hybridized with a trigonal planar geometry. As all the three substituents lie on the same plane, a plane of symmetry for the...
10.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fetus-Specific Hematopoietic Stem Cell Dosimetry Framework for Leukemia-Relevant Target Cells During Prenatal Development.

Physics in medicine and biology·2026
Same author

MIRD Pamphlet No. 34, Part 2: Benchmarking of MIRDct Software for CT Organ Dose Estimation.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Reprogramming of TLR-Ferroptosis Signaling and Immunometabolic Pathways Overcomes Myeloid Suppression to Improve Checkpoint Blockade in Prostate Cancer.

Cancer research·2026
Same author

Dose coefficients for the ICRP pregnant-female mesh-type reference computational phantoms under idealized external exposures to photons.

Journal of radiological protection : official journal of the Society for Radiological Protection·2026
Same author

Lattice peak optimization: a mixed-integer framework for geometry-adaptive lattice radiotherapy.

Physics in medicine and biology·2026
Same author

Tooth enamel dose coefficients of the ICRP adult mesh-type reference computational phantoms for idealized external neutron exposures.

Journal of radiological protection : official journal of the Society for Radiological Protection·2026
Same journal

Overall Survival with [<sup>177</sup>Lu]Lu-PSMA-617 Versus [<sup>177</sup>Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined <sup>18</sup>F-Flotufolastat PSMA PET and mpMRI.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

PSMA PET/CT-Targeted Biopsy in Men with Negative or Equivocal Multiparametric MRI and Exploratory Dynamic Total-Body PET: The FUPERMAN Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Erratum.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

Live from 2026 SNMMI Annual Meeting in Los Angeles!

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same journal

CAR T-Cell Therapy for Cancer: Updates and Challenges for Response Assessment.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.6K

MIRD Pamphlet No. 34, Part 1: MIRDct-A Customizable Software Tool for CT Dosimetry.

Juan Camilo Ocampo Ramos1,2, Cameron Kofler3, Robert Dawson4

  • 1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|February 12, 2026
PubMed
Summary
This summary is machine-generated.

A new software tool, MIRDct, provides accurate CT dosimetry for radiology and nuclear medicine. It helps optimize imaging protocols and assess patient radiation dose, ensuring safety and regulatory compliance.

Keywords:
CT dosimetrycomputational phantomsdosimetry softwareorgan-absorbed dose

More Related Videos

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.5K
Use of Three-Dimensional Imaging Reconstruction Software as a Training Tool for Cranial Vena Cava Venipuncture in the Ferret
04:18

Use of Three-Dimensional Imaging Reconstruction Software as a Training Tool for Cranial Vena Cava Venipuncture in the Ferret

Published on: July 15, 2025

1.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities
06:51

Dosimetry for Cell Irradiation using Orthovoltage 40-300 kV X-Ray Facilities

Published on: February 20, 2021

5.6K
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.5K
Use of Three-Dimensional Imaging Reconstruction Software as a Training Tool for Cranial Vena Cava Venipuncture in the Ferret
04:18

Use of Three-Dimensional Imaging Reconstruction Software as a Training Tool for Cranial Vena Cava Venipuncture in the Ferret

Published on: July 15, 2025

1.2K

Area of Science:

  • Medical Physics
  • Radiological Sciences
  • Nuclear Medicine

Background:

  • Computed tomography (CT) is crucial in diagnostic radiology and hybrid imaging (PET/CT, SPECT/CT).
  • CT radiation doses can be significant, necessitating accurate dosimetry for protocol optimization.
  • Robust tools are required for patient radiation dose assessment in clinical and research settings.

Purpose of the Study:

  • To develop MIRDct, a software tool for organ model-based CT dosimetry and radiation risk assessment.
  • To provide accurate dose estimates for radiology and nuclear medicine applications.
  • To support CT protocol optimization and regulatory compliance.

Main Methods:

  • MIRDct utilizes user-defined patient characteristics, scanner specifications, and technique parameters.
  • It employs a library of 24 mesh-type phantoms representing diverse patient populations.
  • A precomputed Monte Carlo-based dose-coefficient database enables rapid calculation of various dose metrics.

Main Results:

  • MIRDct provides organ-level dose estimates, effective dose, dose-length product, and size-specific dose estimates.
  • It calculates risk-related metrics like detriment-weighted dose and lifetime attributable risk.
  • Benchmarking showed reasonable agreement with other dosimetry codes (4%-30% differences for effective dose).

Conclusions:

  • MIRDct offers a transparent, spreadsheet-based implementation for CT dosimetry and risk assessment.
  • The software aids in optimizing CT protocols, enhancing patient safety, and supporting quality assurance.
  • MIRDct is a valuable tool for accurate CT dosimetry in clinical practice and research.