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Patient-Reported Outcome Measures Used in Primary Hyperparathyroidism: A Scoping Review.

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Summary
This summary is machine-generated.

Patient-reported outcome measures (PROMs) are crucial for assessing primary hyperparathyroidism (PHPT) research. This review found many studies missed opportunities to use PROMs, highlighting a need for better health-related quality of life measurement in PHPT.

Keywords:
HyperparathyroidismParathyroidectomyPatient-reported outcome measuresQuality of lifeQuestionnaireSurvey

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Area of Science:

  • Endocrinology
  • Clinical Research Methodology
  • Health Outcomes Research

Background:

  • Standardized patient-reported outcome measures (PROMs) are essential for evaluating interventions and disease patterns.
  • The utilization of PROMs in primary hyperparathyroidism (PHPT) research remains unclear.
  • This scoping review aimed to map the current use of PROMs in PHPT patient research.

Purpose of the Study:

  • To delineate the landscape of PROMs employed in research involving patients with PHPT.
  • To identify the frequency and types of PROMs used in PHPT studies.
  • To assess the validity of PROMs for use in the PHPT population.

Main Methods:

  • Systematic search of six databases for primary research articles.
  • Inclusion of studies involving PHPT patients that utilized PROMs.
  • Independent review and collation of study and PROM characteristics.

Main Results:

  • Out of 243 studies examined, 96 (50.3%) used at least one PROM.
  • The 36-item Short Form Health Survey, Parathyroidectomy Assessment of Symptoms, and Beck Depression Inventory were the most common PROMs.
  • Only three PROMs demonstrated validity evidence for use in PHPT patients; others were validated in different populations.

Conclusions:

  • Significant opportunities exist to enhance the rigor of health-related quality of life assessments in PHPT research.
  • Future research should prioritize the appropriate application of PROMs to ensure valid findings.
  • Improved PROM utilization is critical for advancing the understanding and management of PHPT.