Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

816
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
816
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.0K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.0K
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.6K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.6K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

651
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
651
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.1K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Rare Presentation of Babesia-Associated Splenic Infarction in an Immunocompetent Young Male With Mild Parasitemia.

Case reports in medicine·2026
Same author

Evaluating the Efficacy of Eravacycline and Omadacycline against Extensively Drug-Resistant <i>Acinetobacter baumannii</i> Patient Isolates.

Antibiotics (Basel, Switzerland)·2022
Same author

Evaluating the Effectiveness of Hospital Antiseptics on Multidrug-Resistant <i>Acinetobacter baumannii</i>: Understanding the Relationship between Microbicide and Antibiotic Resistance.

Antibiotics (Basel, Switzerland)·2022
Same journal

Facial Lichen Planopilaris Mimicking Melasma: A Case Report Emphasizing the Value of Clinicopathologic Correlation.

Case reports in dermatological medicine·2026
Same journal

Overlapping Hyperpigmented and Poikilodermatous Mycosis Fungoides.

Case reports in dermatological medicine·2026
Same journal

Leukemia Cutis Exhibiting the Koebner Phenomenon: A Rare Clinical Presentation of Acute Myeloid Leukemia.

Case reports in dermatological medicine·2026
Same journal

Severe Eczema Herpeticum With Ocular Involvement Leading to Orbital Cellulitis: A Pediatric Case Report.

Case reports in dermatological medicine·2026
Same journal

LC-OCT Features of Confluent and Reticulated Papillomatosis of Gougerot-Carteaud Syndrome.

Case reports in dermatological medicine·2026
Same journal

Secondary Syphilis With Concomitant Bullous Pemphigoid: A Case Report.

Case reports in dermatological medicine·2026
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
06:44

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain

Published on: June 23, 2009

20.4K

Cutaneous Tuberculosis Presenting as a Chronic Dermatologic Disorder.

Olivia Spina1, Henry Fraimow1,2, Justin Green1,3

  • 1Cooper Medical School of Rowan University, Camden, New Jersey, USA, rowan.edu.

Case Reports in Dermatological Medicine
|February 13, 2026
PubMed
Summary
This summary is machine-generated.

Diagnosing cutaneous tuberculosis (CTB) can be challenging due to varied presentations. Interferon-gamma release assays (IGRAs) aid in diagnosing paucibacillary forms of this skin tuberculosis.

Keywords:
antituberculous therapycase reportcutaneous tuberculosisdiagnosis

More Related Videos

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

17.0K
Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
10:06

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence

Published on: February 26, 2018

7.8K

Related Experiment Videos

Last Updated: Feb 14, 2026

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
06:44

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain

Published on: June 23, 2009

20.4K
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
11:35

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

Published on: December 8, 2010

17.0K
Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
10:06

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence

Published on: February 26, 2018

7.8K

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Cutaneous tuberculosis (CTB) is a rare extrapulmonary form of tuberculosis.
  • Tuberculosis verrucosa cutis (TBVC) presents diagnostic challenges due to paucibacillary nature and resemblance to other skin conditions.

Purpose of the Study:

  • To highlight the diagnostic utility of interferon-gamma release assays (IGRAs) in challenging cases of cutaneous tuberculosis.
  • To discuss the management difficulties and therapeutic strategies for TBVC.

Main Methods:

  • Case report of a 73-year-old woman with a 10-year history of misdiagnosed skin lesions.
  • Utilized QuantiFERON-TB Gold test when traditional methods (stains, cultures, PCR) were negative.
  • Documented adverse drug reactions to standard antituberculosis therapy (HRZE).

Main Results:

  • A positive QuantiFERON-TB Gold test confirmed the diagnosis of TBVC despite negative microbiological tests.
  • The patient experienced adverse drug reactions to pyrazinamide and rifampin.
  • An alternative treatment regimen led to improved tolerability and clinical resolution.

Conclusions:

  • IGRAs are valuable tools for diagnosing paucibacillary cutaneous tuberculosis.
  • Managing TBVC requires vigilance for diagnostic pitfalls and careful consideration of adverse drug reactions.
  • Individualized treatment approaches are crucial for effective TBVC management.