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Extraction of Plant-based Capsules for Microencapsulation Applications
Published on: November 9, 2016
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Plant-Based Exosomes: Insights and Therapeutic Applications
Chandrika Kumari Bodala1, Aliya Parveen1, Bhagya Lakshmi Gogireddy1
1GITAM School of Pharmacy, GITAM Deemed to be University, Rushikonda, Visakhapatnam-530045, A.P., India.
Critical Reviews in Therapeutic Drug Carrier Systems
|February 13, 2026
Summary
Plant-derived exosomes show promise as natural nanocarriers for drug delivery due to their biocompatibility and therapeutic potential. This review explores their sources, isolation, characterization, and applications in treating various disorders.
Area of Science:
- Biotechnology
- Nanomedicine
- Pharmacology
Background:
- Exosomes are nano-sized extracellular vesicles involved in intercellular communication.
- Initially discovered in mammals, exosomes are now recognized as valuable natural carriers for bioactive compounds.
- Plant-derived exosomes offer unique advantages for drug delivery systems.
Purpose of the Study:
- To review the biological components, biogenesis, and sources of plant exosomes.
- To examine methodologies for isolating, purifying, and characterizing plant exosomes.
- To explore the therapeutic applications and challenges of plant-derived exosomes in drug delivery.
Main Methods:
- Literature review of studies on plant exosome biogenesis, isolation, and characterization.
- Analysis of techniques for evaluating exosome biological components (proteins, lipids).
- Discussion of research on plant exosome applications in drug delivery for various disorders.
Main Results:
- Plant exosomes can be sourced from various plant parts (fruits, vegetables, leaves).
- They possess therapeutic effects like anticancer, anti-inflammatory, and antioxidant properties.
- Plant exosomes demonstrate biocompatibility, stability, and targeted delivery capabilities for drug transport.
Conclusions:
- Plant-derived exosomes represent a promising platform for advanced drug delivery systems.
- Further research is needed to address challenges in isolation, standardization, and drug loading.
- Optimizing plant exosome utilization can enhance therapeutic outcomes for diverse diseases.
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