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Updated: Feb 15, 2026

Synthesis, Characterization, and Functionalization of Hybrid Au/CdS and Au/ZnS Core/Shell Nanoparticles
Published on: March 2, 2016
A new and low-cost magneto-sensing strategy based on multi-functional core-shell gold nanoparticles towards
Elif Burcu Aydın1, Muhammet Aydın1, Mustafa Kemal Sezgintürk2
1Tekirdağ Namık Kemal University, Scientific and Technological Research Center, Tekirdağ, Turkey.
Abstract:
In this research, an innovative, highly selective, and label-free impedimetric biosensor based on the magnetosensing strategy was designed for the detection of bis(2-ethylhexyl)phthalate (DEHP). The magnetosensing platform was prepared using multi-functional core-shell gold magnetic nanoparticles (conjugated thiophene copolymer (P(TNhs-co-Edot)) decorated Fe3O4@Au MNPs) as the matrix material and the DEHP aptamer as the biorecognition element. The DEHP analytes interacted directly with a fixed quantity of DEHP aptamers on the Fe3O4@Au/P(TNhs-co-Edot) MNPs and caused changes in electrochemical response. This specific interaction caused an increase in the charge transfer resistance (Rct) of the electrode, which was employed as a useful indicator to determine the DEHP concentration. The aptasensor displayed an impedimetric response to DEHP within a concentration range of 1-500 pg/mL with a detection limit (LOD) of 0.30 pg/mL. The biosensor displayed acceptable repeatability (low relative standard deviations (RSDs), < 5.08) and reproducibility (low RSDs, <5.80), good selectivity, and long storage stability (71.52 % activity after 7 weeks). Moreover, this approach was employed for the detection of migrated DEHP in common plastic items into water sources, real water, and food samples. The recoveries obtained using the biosensor ranged from 95.51 % to 104.16 %, and the RSDs were less than 5.64 %. Our findings displayed that the current aptasensor was a promising option for use in migration tests.
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