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Updated: Feb 16, 2026

High-Accuracy Correction of 3D Chromatic Shifts in the Age of Super-Resolution Biological Imaging Using Chromagnon
Published on: June 16, 2020
Chromatic and spherical aberration correction with hexapole and quadrupole fields
Shigeyuki Morishita1, Hidetaka Sawada2, Norihiro Okoshi2
1JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-8558, Japan; JEOL (U.K.) Limited, 1-2 Silver Court, Watchmead, Welwyn Garden City, Hertfordshire AL7 1LT, UK; Department of Materials, University of Oxford, Parks Road, Oxford, Oxfordshire OX1 3PH, UK; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0QX, UK.
Abstract:
We report the development of a chromatic and spherical aberration corrector based on combinations of hexapole and quadrupole fields. Thick hexapole fields are used to generate negative third order spherical aberration and to correct residual axial and off-axial aberrations. As an alternative to the use of round transfer lenses placed between the hexapoles, a quadrupole multiplet producing superimposed electric and magnetic quadrupole fields is used to produce negative chromatic aberration. This quadrupole multiplet also functions as a transfer doublet within the corrector. The simultaneous correction of chromatic and spherical aberrations using this corrector design is described, and a resolution improvement is demonstrated for cases where the energy spread is limiting.
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