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Updated: Feb 16, 2026

High-Accuracy Correction of 3D Chromatic Shifts in the Age of Super-Resolution Biological Imaging Using Chromagnon
Published on: June 16, 2020
Chromatic and spherical aberration correction with hexapole and quadrupole fields.
Shigeyuki Morishita1, Hidetaka Sawada2, Norihiro Okoshi2
1JEOL Ltd., 3-1-2 Musashino, Akishima, Tokyo 196-8558, Japan; JEOL (U.K.) Limited, 1-2 Silver Court, Watchmead, Welwyn Garden City, Hertfordshire AL7 1LT, UK; Department of Materials, University of Oxford, Parks Road, Oxford, Oxfordshire OX1 3PH, UK; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0QX, UK.
This study introduces a novel corrector for chromatic and spherical aberrations using hexapole and quadrupole fields. The new design enhances resolution, particularly when energy spread is a limiting factor in imaging.
Area of Science:
- Physics
- Optical Engineering
- Electron Microscopy
Background:
- Aberrations limit resolution in electron microscopy.
- Chromatic and spherical aberrations are key challenges.
- Existing correctors often require complex designs or multiple components.
Purpose of the Study:
- To develop an advanced corrector for simultaneous chromatic and spherical aberration correction.
- To improve imaging resolution in electron microscopy.
- To offer a more integrated and efficient aberration correction solution.
Main Methods:
- Utilized combinations of hexapole and quadrupole fields.
- Employed thick hexapole fields for negative spherical aberration.
- Integrated a quadrupole multiplet for negative chromatic aberration and transfer doublet function.
Main Results:
- Successfully designed and implemented a corrector for simultaneous aberration correction.
- Demonstrated significant resolution improvement in imaging.
- Showcased effectiveness in cases limited by energy spread.
Conclusions:
- The developed corrector effectively addresses both chromatic and spherical aberrations.
- This design offers a viable alternative for enhancing electron microscope performance.
- The integrated approach simplifies corrector design and improves imaging quality.
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