Related Experiment Video
Updated: Feb 16, 2026
08:52
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
17.8K
Factors Associated With Prolonged Inpatient Stay in Patients Undergoing Outpatient Allogeneic Stem Cell
Edward Koo1, Connor Prince1, David Allan1
1Transplant and Cellular Therapy Program, Division of Hematology, Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.
Transplantation and Cellular Therapy
|February 14, 2026
Summary
Outpatient allogeneic hematopoietic stem cell transplantation (HCT) is safe and feasible, saving hospital days. Female sex, low hemoglobin, and certain transplant factors predict longer inpatient stays, aiding resource management.
Area of Science:
- Hematology
- Transplantation Medicine
- Oncology
Background:
- Allogeneic hematopoietic stem cell transplantation (HCT) is increasingly performed in outpatient settings.
- Limited data exists on factors influencing prolonged inpatient stays for outpatient allogeneic HCT patients.
Purpose of the Study:
- To identify parameters associated with prolonged inpatient stays in patients undergoing allogeneic HCT within an outpatient day hospital model.
Main Methods:
- Retrospective analysis of 213 patients undergoing outpatient allogeneic HCT (July 2021-July 2024).
- Mann-Whitney U and Chi-squared tests for univariate analysis.
- Binary logistic regression for multivariate analysis to identify factors associated with >5 days inpatient admission.
Main Results:
- Female sex, pre-transplant hemoglobin <100g/L, HCT-CI >2, non-fludarabine/busulfan conditioning regimens, and ABO mismatch were linked to prolonged inpatient stays.
- 13.3% of patients had no inpatient admission; 50.7% had one admission.
- Average savings of 22 inpatient bed-days per patient were observed.
Conclusions:
- Outpatient allogeneic HCT via a day hospital model is a viable and cost-effective approach.
- Identifying factors for prolonged admissions improves patient education and resource allocation.
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