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Related Concept Videos

Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

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Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

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Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
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Cofactors and Coenzymes01:27

Cofactors and Coenzymes

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Enzymes require additional components for proper function. There are two such classes of molecules: cofactors and coenzymes. Cofactors are metallic ions and coenzymes are non-protein organic molecules. Both of these types of helper molecule can be tightly bound to the enzyme or bound only when the substrate binds.
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PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS
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Vitamin E in dermatology.

Marcia Ramos-E-Silva1, Claudia Camargo1, Renata Cavalcante1

  • 1Sector of Dermatology and Post-Graduation Course in Dermatology, School of Medicine and University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Clinics in Dermatology
|February 14, 2026
PubMed
Summary
This summary is machine-generated.

Vitamin E, encompassing tocopherol and tocotrienol, is crucial for skin health and stress resistance. Research is ongoing to fully understand its photoprotective and anti-tumorigenic benefits in dermatology.

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Area of Science:

  • Dermatology and Nutritional Science

Background:

  • Nutrition plays a vital role in skin rejuvenation, recovery, and regeneration.
  • Vitamin E, a liposoluble antioxidant, has a long history in dermatology but requires further research regarding its photoprotective and anti-tumorigenic effects.
  • Vitamin E includes tocopherol (TP) and tocotrienol (T3), with T3 exhibiting superior antioxidant capacity due to its unsaturated side-chain.

Purpose of the Study:

  • To explore the role of oral and topical Vitamin E in dermatologic and systemic conditions.
  • To highlight the stress-protective and homeostatic benefits of Vitamin E.

Main Methods:

  • Review of existing literature on Vitamin E's dermatological applications.
  • Discussion of the biochemical differences between tocopherol and tocotrienol.
  • Analysis of studies investigating Vitamin E's response to various stressors.

Main Results:

  • Vitamin E demonstrates significant benefits in skin care, including rejuvenation and recovery.
  • Emerging evidence suggests Vitamin E enhances stress protection, normalizes cellular homeostasis, and increases resistance to cellular damage.
  • Tocotrienol (T3) shows a higher antioxidant effect compared to tocopherol (TP).

Conclusions:

  • Vitamin E is essential for skin health and offers protection against various stressors.
  • Further research is needed to fully elucidate the photoprotective and anti-tumorigenic properties of Vitamin E.
  • Both oral and topical Vitamin E show promise in improving various dermatologic and systemic conditions.