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Real-Time Tracking of Ion Migration Process at the Single-Nanoparticle Level.

Bin Bin Chen^1,2, Da Jun Wu¹, Zi Yue Jin¹

¹School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.

Analytical Chemistry

|February 16, 2026

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This summary is machine-generated.

Researchers visualized silver ion migration in selenium nanoparticles using dark-field microscopy. This transformation allows for real-time tracking and creates a nanomaterial for Ag+ detection and cancer theranostics.

Area of Science:

Materials Science
Nanotechnology
Physical Chemistry

Background:

Ion migration in nanomaterials significantly impacts their photophysical properties.
Real-time monitoring of ion migration within individual nanoparticles is crucial but challenging.

Purpose of the Study:

To achieve in situ visualization of ion migration at the single-nanoparticle level.
To develop a method for tracking crystal phase transformations in nanomaterials.

Main Methods:

Utilized a dark-field microscopy (DFM) platform for real-time optical tracking.
Investigated the interaction of silver ions (Ag+) with selenium nanoparticles (SeNPs).

Main Results:

Observed the phase transformation of SeNPs to cubic Ag2Se upon Ag+ ion permeation.

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Demonstrated a distinct color shift in scattered light (green to red) indicating the transformation.

Established Ag2Se as a sensitive probe for Ag+ detection and a photothermal nanoreagent.

Conclusions:

Provided direct visual insight into ion migration and crystal phase transformation dynamics.
Established a general strategy for tracking ion migration, aiding in the design of functional nanomaterials.
Highlighted the potential of Ag2Se nanomaterials for cancer theranostics.