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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Related Experiment Video

Updated: Feb 17, 2026

High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network
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Early Postmortem Changes in Pancreas: An Antemortem and Postmortem Computed Tomography Study.

Terumi Umeda1, Shohei Inui2, Satori Gonoi3

  • 1Radiology, Shimane University, Izumo, JPN.

Cureus
|February 16, 2026
PubMed
Summary
This summary is machine-generated.

Early postmortem imaging shows a significant decrease in healthy pancreatic density and volume. These findings are crucial for interpreting postmortem computed tomography (PMCT) scans of the pancreas.

Keywords:
computed tomographyforensic radiologypancreaspostmortem computed tomographypostmortem imaging

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Area of Science:

  • Forensic radiology
  • Medical imaging
  • Pancreatic imaging

Background:

  • Investigating early postmortem changes in the pancreas is essential for accurate interpretation of imaging findings.
  • Longitudinal analysis across antemortem computed tomography (AMCT) and postmortem computed tomography (PMCT) provides valuable insights into these changes.

Purpose of the Study:

  • To longitudinally investigate early postmortem changes in the healthy pancreas using computed tomography (CT).
  • To quantify changes in pancreatic volume and density from antemortem to postmortem imaging.

Main Methods:

  • Adult patients with healthy pancreases confirmed by autopsy were included.
  • Unenhanced AMCT and PMCT scans were analyzed.
  • Pancreatic volume, density, and histogram parameters (skewness, kurtosis) were measured and statistically compared.

Main Results:

  • A significant decrease in pancreatic density (AMCT: 31.2 HU vs. PMCT: 26.6 HU) was observed.
  • Pancreatic volume also significantly reduced (AMCT: 63.8 ml vs. PMCT: 56.8 ml).
  • Histogram skewness of pancreatic density increased significantly postmortem, while kurtosis showed no significant difference.

Conclusions:

  • Healthy pancreatic density and volume significantly decrease in the early postmortem period.
  • These quantitative changes provide a baseline for interpreting normal postmortem pancreatic imaging.
  • Findings aid in differentiating postmortem changes from pathological conditions in forensic and clinical radiology.