Related Experiment Video

Updated: Feb 17, 2026

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult
09:39

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult

Published on: April 26, 2018

9.2K

[Consequences of congenital COVID-19 on the cognitive development of affected children]

Marta Martinez-Morga1, Daniel Garrigos1, Salvador Martinez-Morga1

  • 1Instituto de Neurociencias UMH-CSIC. Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL-ISCIII), Alicante, España.

Medicina
|February 16, 2026
PubMed

Insights

Congenital COVID-19, or prenatal SARS-CoV-2 exposure, is linked to a tenfold increase in developmental delay in newborns. Understanding these neurodevelopmental impacts is crucial for early intervention and long-term child health monitoring.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Developmental Biology

Background:

  • Congenital COVID-19 results from maternal SARS-CoV-2 infection during pregnancy.
  • Vertical transmission is infrequent, but prenatal exposure impacts fetal neurological development.
  • Maternal immune response to SARS-CoV-2 also affects neurodevelopment.

Purpose of the Study:

  • To review the potential cognitive consequences of congenital COVID-19.
  • To understand the implications for early neurological development.
  • To examine pathogenic mechanisms behind neurodevelopmental alterations.

Main Methods:

  • Literature review of clinical and epidemiological evidence.
  • Analysis of studies on neonates exposed to SARS-CoV-2 in utero.
  • Examination of pathogenic mechanisms of neurodevelopmental alterations.

Main Results:

  • Neonates exposed to congenital COVID-19 show a tenfold higher incidence of developmental delay.
  • Prenatal SARS-CoV-2 exposure has significant implications for early neurological development.
  • Maternal immune response contributes to neurodevelopmental changes.

Conclusions:

  • Congenital COVID-19 poses risks for neurodevelopmental outcomes.
  • Early intervention strategies are essential for affected children.
  • Further research into pathogenic mechanisms is needed for long-term monitoring.

Keywords:
congenital COVID‐19developmental delayneurodevelopmentpost‐COVID‐19

More Related Videos

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

11.9K
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

20.5K

Related Concept Videos

Language and Cognition01:27

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
829
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
613
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.3K
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.3K
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
1.0K
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
671