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Related Experiment Video

Updated: Feb 18, 2026

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MAGNETIC INTRAOCULAR FOREIGN BODY INJURIES: Intravitreal Antibiotic Prophylaxis, Endophthalmitis Risk and Prognostic

Yuan Wen1, Tingting Wang2, Linbo Liu1

  • 1Department of Ophthalmology, Hebei Medical University, Shijiazhuang, Hebei, China ; and.

Retina (Philadelphia, Pa.)
|February 16, 2026
PubMed
Summary
This summary is machine-generated.

Prophylactic intravitreal antibiotics significantly reduced endophthalmitis after posterior segment magnetic intraocular foreign body (IOFB) injuries. Key risk factors for infection and poor outcomes include lens capsule rupture and larger IOFBs.

Keywords:
endophthalmitisintraocular foreign bodyopen globe injuryprognosisrisk factors

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Experimental Glaucoma Induced by Ocular Injection of Magnetic Microspheres
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Area of Science:

  • Ophthalmology
  • Infectious Diseases

Background:

  • Posterior segment intraocular foreign bodies (IOFBs) pose a risk of severe complications, including endophthalmitis.
  • Magnetic IOFBs require specific management strategies to prevent infection and preserve vision.

Purpose of the Study:

  • To evaluate the efficacy of prophylactic intravitreal antibiotics in preventing endophthalmitis following posterior segment magnetic IOFB injuries.
  • To identify risk factors for endophthalmitis and prognostic factors influencing visual outcomes in these cases.

Main Methods:

  • Retrospective analysis of patients with posterior segment magnetic IOFBs treated between 2014 and 2022.
  • Comparison of endophthalmitis rates between a cohort receiving primary repair plus intravitreal antibiotics (2016-2022) and a historical cohort receiving only primary repair (2014-2016).

Main Results:

  • The incidence of endophthalmitis was significantly lower in the recent cohort (4.7%) compared to the previous cohort (13.6%).
  • Lens capsule rupture and IOFB size > 2 mm were identified as significant risk factors for endophthalmitis.
  • Lens capsule rupture, vitreous hemorrhage, retinal detachment, choroidal detachment, and IOFB size > 2 mm were predictors of poor visual outcome.

Conclusions:

  • Prophylactic intravitreal antibiotics are effective in reducing endophthalmitis rates in posterior segment magnetic IOFB injuries.
  • Early identification and management of risk factors like lens capsule rupture and IOFB size are crucial for improving patient prognosis.