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Related Experiment Video

Updated: Feb 18, 2026

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Racial Differences in Dermatologic Treatment for Adolescents With PCOS-Related Acne Vulgaris.

Samantha Garcia1, Brandi Kenner-Bell1,2

  • 1Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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|February 16, 2026
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Summary

Racial and ethnic disparities in acne treatment exist for adolescents with polycystic ovary syndrome (PCOS). Hispanic and Black adolescents with PCOS received fewer prescriptions for key acne medications compared to others.

Keywords:
acne vulgariscombined oral contraceptivesdiversity, equity, and inclusionhealth equityhormonal therapypolycystic ovary syndromespironolactone

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Area of Science:

  • Dermatology
  • Endocrinology
  • Health Services Research

Background:

  • Polycystic ovary syndrome (PCOS) is a common endocrine disorder impacting adolescent women.
  • Acne vulgaris frequently co-occurs with PCOS during adolescence.
  • Existing research highlights racial/ethnic disparities in adult acne treatment, but adolescent PCOS acne management remains understudied.

Purpose of the Study:

  • To evaluate racial and ethnic differences in acne treatment patterns among adolescents diagnosed with PCOS.
  • To identify specific acne therapies with differential prescription rates across racial and ethnic groups in this population.

Main Methods:

  • Retrospective chart review of female patients under 18 with PCOS and acne vulgaris at an academic medical center (2012-2022).
  • Data extraction included demographics, clinical details, and acne treatment records.
  • Statistical analyses (chi-squared, Fisher's exact, multivariable logistic regression) assessed group differences and associations, adjusting for covariates.

Main Results:

  • The study included 138 adolescents; most had moderate acne.
  • Significant differences in insurance type and interpreter use were observed across racial/ethnic groups.
  • Hispanic adolescents had significantly lower odds of receiving spironolactone, combined oral contraceptives (COC), and isotretinoin.
  • Black adolescents had significantly lower odds of receiving topical antibiotic prescriptions.

Conclusions:

  • Racial and ethnic disparities in acne treatment are evident among adolescents with PCOS.
  • Hispanic and Black adolescents experience reduced access to specific, effective acne treatments.
  • These disparities persist even after accounting for acne severity, insurance status, and interpreter needs, warranting further investigation into equitable care.