Related Experiment Video

Updated: Feb 18, 2026

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

11.6K

Pediatric RSV-Protection and Social Risk in Three Academic Primary Care Centers

Mary Carol Burkhardt1, Melissa E Day2, Anne K Jackson3

  • 1Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Academic Pediatrics
|February 16, 2026
PubMed

Insights

Respiratory Syncytial Virus (RSV) protection increased in infants during the 2023-24 and 2024-25 seasons. Infants with positive social risk factors were more likely to receive RSV protection, indicating potential for equitable health outcomes.

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health
  • Health Equity

Background:

  • Respiratory Syncytial Virus (RSV) poses a significant health burden on infants.
  • The availability of RSV therapeutics presents an opportunity to improve protection rates.
  • Understanding disparities in access to preventative measures is crucial for equitable health outcomes.

Purpose of the Study:

  • To investigate the association between social risk and Respiratory Syncytial Virus (RSV) protection in infants.
  • To analyze trends in RSV protection and its relationship with social determinants of health during the 2023-24 and 2024-25 seasons.
  • To assess the impact of novel RSV therapeutics on equitable protection among diverse infant populations.

Main Methods:

  • Retrospective study utilizing electronic health records from three pediatric primary care practices.
  • Inclusion criteria: infants under 8 months during RSV seasons, with documented RSV protection status (nirsevimab or maternal vaccination).
  • Statistical analysis included Chi-squared tests and multivariable logistic regression to assess associations between social risk, sociodemographic factors, and RSV protection.

Main Results:

  • RSV protection increased from 47.7% in 2023-24 to 60.5% in 2024-25 (p<0.001).
  • Infants with positive social risk screens were more likely to receive RSV protection in both seasons (p=0.018 in 2023-24; p=0.007 in 2024-25).
  • After adjustment, positive social risk remained associated with higher odds of RSV protection (OR 1.25-1.36).

Conclusions:

  • RSV protection rates significantly improved between the 2023-24 and 2024-25 seasons.
  • Social risk factors were positively associated with receiving RSV protection, suggesting these therapeutics may be reaching vulnerable populations.
  • These findings support the potential for novel RSV therapeutics to promote more equitable health outcomes.
Abstract

Keywords:
nirsevimabpediatricsprimary health carerespiratory syncytial virus infectionsrespiratory syncytial virus vaccinessocial determinants of health

More Related Videos

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

8.4K
Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

17.3K

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
6.4K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
2.0K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.9K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K
Specialized Care Centers and Settings-II01:30

Specialized Care Centers and Settings-II

Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
1.3K
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.6K