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Published on: September 15, 2017
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Design and Biomedical Applications of Bioactive Clusters.
Di Liu1, Hao Wang1, Xiao-Dong Zhang1
1Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|February 17, 2026
Summary
Bioactive clusters show tunable properties for biomedical uses like therapy and imaging. This review covers their design, diverse activities, and future potential in medicine.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Bioactive clusters possess tunable structures and diverse biological activities.
- These properties enable applications in disease therapy, bioimaging, and drug delivery.
Purpose of the Study:
- To review the classification and bioactivities of bioactive clusters.
- To elucidate rational design strategies for bioactive clusters.
- To highlight their therapeutic and imaging applications.
Main Methods:
- Literature review of bioactive clusters.
- Analysis of their biocatalytic, optical, photothermal, and photodynamic effects.
- Summary of therapeutic applications (tumors, oxidative stress, inflammation) and imaging modalities.
Main Results:
- Bioactive clusters demonstrate significant potential in treating tumors and inflammation-related diseases.
- Their biocatalysis and anti-inflammatory activities are key therapeutic mechanisms.
- Advanced imaging capabilities include noninvasive imaging and 3D visualization, supporting integrated therapy.
Conclusions:
- Bioactive clusters offer versatile platforms for advanced biomedical applications.
- Rational design and activity programming are crucial for optimizing their use.
- Future development, including AI-driven design and biosafety evaluation, will accelerate clinical translation.
