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Urosepsis due to obstructive stones: Epidemiological data from a population-based study in Sweden
Hjalmar Svensson1,2, Lars Grenabo1, Klas Lindqvist1,3
1Department of Urology, Sahlgrenska Academy University of Gothenburg Gothenburg Sweden.
Urinary tract infections caused by ureteric stones are life-threatening, particularly in the elderly. This condition requires intensive care in severe cases and can be fatal, highlighting the need for better epidemiological data.
Area of Science:
- Urology
- Infectious Diseases
- Epidemiology
Background:
- Urinary tract infections (UTIs) secondary to ureteric stones are a serious health concern.
- Few epidemiological studies exist on the incidence and clinical course of obstructive UTIs.
Purpose of the Study:
- To describe the population-based incidence, epidemiology, and clinical outcomes of UTIs caused by ureteric stone obstruction.
- To provide data on a life-threatening condition with limited prior epidemiological reporting.
Main Methods:
- Retrospective cohort study using Swedish National Patient Register and local hospital databases.
- Identified adult patients with International Classification of Disease 10th revision codes for urolithiasis and UTI.
- Analyzed data from 315 patients over two years, excluding those with ongoing treatment, non-significant infection, or no obstruction.
Main Results:
- The incidence of acute obstructive UTI was 11.8 per 100,000 inhabitants annually.
- The median patient age was 68 years, with 56% being women.
- 16% required ICU admission, and 3% died, with deaths attributed to sepsis or delays in treatment.
Conclusions:
- Acute obstructive UTI primarily impacts the elderly population.
- The clinical course is variable, with severe cases necessitating intensive care and carrying a risk of mortality.
- Findings underscore the severity and epidemiological significance of this condition.
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