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Related Concept Videos

Gastric Emptying01:16

Gastric Emptying

Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
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Related Experiment Video

Updated: Jun 29, 2026

A Murine Model of Vertical Sleeve Gastrectomy
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Metabolic Reverse Sleeve: Preliminary Results from the First 10 Cases.

Mourad Adala1, Saleh Abujamra2, Adama Sanou3

  • 1Clinique El Manar, Tunis, Tunisia.

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
|February 18, 2026
PubMed
Summary
This summary is machine-generated.

The novel metabolic reversible sleeve (MRS) bariatric procedure shows promising safety in early results. This new approach appears feasible with no major complications in the first 10 patients.

Keywords:
complicationgastric preservationmetabolic reversible sleevesafety

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Area of Science:

  • Bariatric surgery
  • Minimally invasive procedures
  • Gastrointestinal surgery

Background:

  • Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass (RYGB) are effective but have long-term risks.
  • Gastroesophageal reflux and marginal ulcers are known complications of current bariatric surgeries.
  • The metabolic reversible sleeve (MRS) is a new, reversible bariatric procedure designed to preserve gastric anatomy.

Purpose of the Study:

  • To evaluate the safety outcomes of the metabolic reversible sleeve (MRS) procedure.
  • To report on the initial safety data from the first 10 consecutive patients undergoing MRS.
  • To assess perioperative complications and early recovery associated with MRS.

Main Methods:

  • Preoperative assessments included nutritional, psychiatric, and radiological evaluations.
  • The MRS procedure involved laparoscopic gastric bipartition and jejunal bypass, preserving stomach anatomy.
  • Standardized perioperative management and recording of safety outcomes (intraoperative complications, postoperative morbidity, readmissions) were employed.

Main Results:

  • Ten patients (mean BMI 50.74 kg/m² ) underwent successful laparoscopic MRS without conversion.
  • No intraoperative complications, anastomotic leaks, bleeding, or reoperations occurred.
  • Patients were discharged between postoperative days 2-3 with normal lab values; mild nausea in 2 patients resolved spontaneously.

Conclusions:

  • The metabolic reversible sleeve (MRS) appears to be a safe and feasible bariatric procedure in this initial series.
  • No major perioperative complications were observed in the first 10 patients.
  • Further research with larger cohorts and long-term follow-up is needed to confirm MRS safety and efficacy.