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Updated: Feb 20, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
Expanding the Contemporary Paradigm of Sleeve Gastrectomy: Innovation, Prevention, and Physiological Preservation
Marius Nedelcu1,2, Mariano Palermo3
1ELSAN, Clinique Bouchard, Marseille, France.
Abstract:
Over the past two decades, sleeve gastrectomy has become the most widely performed bariatric operation, yet growing long-term evidence has highlighted limitations such as weight recurrence, gastroesophageal reflux, and declining metabolic durability, prompting a shift toward refining rather than abandoning sleeve-based strategies. The articles in this special issue collectively demonstrate how thoughtful innovations-ranging from metabolic enhancements and reflux-preserving solutions to reversible procedures and preventive diagnostic measures-can expand the therapeutic scope of sleeve gastrectomy while maintaining physiological continuity and minimizing long-term morbidity. Together, they articulate a unifying vision for the future of bariatric surgery: individualized, adaptable, and physiology-respecting interventions that prioritize durable outcomes and quality of life over increasingly radical anatomical alteration.
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