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Updated: Feb 20, 2026

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Draft genome sequence of multidrug-resistant Escherichia coli isolated from retail chicken liver in Kosovo

Anahita Ghorbani Tajani1, Afrim Hamidi2, Aniket Sharma1

  • 1Department of Animal Science, University of Wyoming, Laramie, Wyoming, USA.

Microbiology Resource Announcements
|February 18, 2026
PubMed

Insights

The draft genome of multidrug-resistant Escherichia coli UA1 was sequenced from chicken liver. This study reveals key antimicrobial resistance genes and plasmids, highlighting food chain contamination risks.

Area of Science:

  • Microbiology
  • Genomics
  • Food Safety

Background:

  • Multidrug-resistant bacteria pose a significant threat to public health.
  • The food chain is a potential reservoir and transmission route for antimicrobial resistance.

Purpose of the Study:

  • To sequence and analyze the draft genome of multidrug-resistant Escherichia coli UA1.
  • To identify antimicrobial resistance genes (ARGs) and plasmids within the isolate.
  • To understand the dissemination of antimicrobial resistance in the food chain.

Main Methods:

  • Whole-genome sequencing of Escherichia coli UA1.
  • Bioinformatic analysis for genome assembly and gene identification.
  • Identification of antimicrobial resistance genes and plasmid sequences.

Main Results:

  • The draft genome of Escherichia coli UA1 was assembled into 86 contigs and 214 scaffolds.
  • Key ARGs including blaEC-18, blaCTX-M-55, and dfrA36 were identified.
  • Presence of virulence genes and plasmids associated with antimicrobial resistance was confirmed.

Conclusions:

  • The genome data provides insights into the genetic basis of multidrug resistance in this E. coli strain.
  • The findings underscore the importance of monitoring antimicrobial resistance in food products.
  • Retail chicken liver can harbor multidrug-resistant bacteria, indicating potential food chain contamination.
Keywords:
Escherichia coliKosovoantimicrobial resistancepublic health surveillance

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