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Mirror-Image D-Core Streptavidin Exhibits Reduced Immunogenicity and Comparable Biodistribution to Natural Core

Masatoshi Suganuma1, Aya Sugyo2, Hitomi Sudo2

  • 1Central Research Laboratories, Sysmex Corporation; Healthcare Science Hub Tokyo, 1-17-8 Shinkiba, Koto-ku, Tokyo 136-0082, Japan.

Chemical & Pharmaceutical Bulletin
|February 18, 2026
PubMed

Keywords:
biodistributiondrug delivery systemenantiomerimmunogenicityproteolysisstreptavidin

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