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Related Experiment Video

Updated: Feb 20, 2026

Continuous Telemetric In Utero Tracheal Pressure Measurements in Fetal Lambs
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Prevention of Stillbirth.

Robert M Silver1, Uma M Reddy2

  • 1Department of Obstetrics and Gynecology, University of Utah, 30 North 1900 East, Helix Building 5th Floor, Salt Lake City, UT 84132, USA.

Clinics in Perinatology
|February 18, 2026
PubMed
Summary

Stillbirth prevention needs better screening for placental insufficiency, the main cause. Interventions like low-dose aspirin and managing maternal health are key, alongside education and prevention bundles.

Keywords:
Antenatal testingBiomarkersFetal growth restrictionFetal movementLow-dose aspirinPlacental insufficiencyRisk stratificationStillbirth prevention

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Perinatal Health

Background:

  • Placental insufficiency is the primary driver of stillbirth in high-resource settings.
  • Conventional risk factors (e.g., maternal age, BMI) offer limited predictive accuracy.
  • Advanced screening methods are crucial for effective stillbirth prevention.

Purpose of the Study:

  • To review current strategies for stillbirth prevention.
  • To highlight the importance of identifying and managing placental insufficiency.
  • To explore effective interventions and future research directions.

Main Methods:

  • Literature review of placental insufficiency and stillbirth prevention strategies.
  • Analysis of traditional versus advanced risk factor assessment.
  • Evaluation of pharmacological and non-pharmacological interventions.

Main Results:

  • Ultrasound, Doppler studies, and biomarkers show potential for universal screening.
  • Low-dose aspirin effectively reduces placental-related complications.
  • Maternal condition management (hypertension, diabetes), fetal movement awareness, and prevention bundles show promise.

Conclusions:

  • A multifaceted approach is essential for stillbirth prevention.
  • Enhanced screening and targeted interventions are needed to reduce stillbirth rates.
  • Further research should focus on refining risk stratification and delivery timing.